Evidence map›Paper›PMID 29158869›Full record

ReviewThe World Allergy Organization journal2017

Otitis media with effusion and atopy: is there a causal relationship?

Mario E Zernotti, Ruby Pawankar, Ignacio Ansotegui, Hector Badellino, Juan Sebastian Croce, Elham Hossny, Motohiro Ebisawa, Nelson Rosario, Mario Sanchez Borges, Yuan Zhang and 1 more

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The World Allergy Organization journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05804123 (Application of LiveSpo Navax® in the Treatment Support of Acute Rhinosinusitis and Acute Otitis Media), which is not on this map. Cited by 34 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 8 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05804123 nacompletednot on this mapstarted 2021, after this paper: background citation

Application of LiveSpo Navax® in the Treatment Support of Acute Rhinosinusitis and Acute Otitis Media

TypeinterventionalSponsorAnabio R&DRan2021 to 2024Enrolled175ConditionsUpper Respiratory Tract InfectionsArms0.9% NaCl physiological saline Nasal-spraying, LiveSpo Navax®, Augmentin 500Mg Tablet, Acetylcysteine, Xylometazoline Nasal
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 8 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Topical and oral steroids for otitis media with effusion (OME) in children.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Pooled it
  4. Antibiotics for otitis media with effusion (OME) in children.The Cochrane database of systematic reviews · 2023
    Pooled it
  5. Adenoidectomy for otitis media with effusion (OME) in children.The Cochrane database of systematic reviews · 2023
    Pooled it
  6. Autoinflation for otitis media with effusion (OME) in children.The Cochrane database of systematic reviews · 2023
    Pooled it
  7. Pooled it
  8. Pooled it
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  11. Review
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 7 countries.

Mario E Zernotti *Department of Otolaryngology, Catholic University of Córdoba, Córdoba, Argentina.
Ruby Pawankar *Department of Pediatrics, Nippon Medical School, Tokyo, Japan.
Ignacio AnsoteguiDepartment of Allergy and Immunology, Hospital Quirón Bizkaia, Erandio, Spain.
Hector BadellinoDepartment of Pediatric Respiratory Medicine, Regional Eastern Clinic, San Francisco, Córdoba, Argentina.
Juan Sebastian CroceCIMER, Catholic University of Córdoba and Croce Institute, Córdoba, Argentina.
Elham HossnyPediatric Allergy Unit, Children's Hospital, Ain Shams University, Cairo, Egypt.
Motohiro EbisawaDepartment of Pediatrics, National Sagamihara Hospital, Sagamihara-shi, Kanagawa Japan.
Nelson RosarioFederal University of Parana, Curitiba, Brazil.
Mario Sanchez BorgesAllergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela.
Yuan ZhangDepartment of Otolaryngology - Head and Neck Surgery, Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Luo ZhangDepartment of Otolaryngology - Head and Neck Surgery, Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China.
Capital Medical University · CNUniversidad Católica de Córdoba · ARAin Shams University Hospital · EGCentro Médico Docente La Trinidad · VEHospital Quirónsalud Barcelona · ESNational Sagamihara Hospital · JPNippon Medical School · JPUniversidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Otitis Media with Effusion (OME) is an inflammatory condition of the middle ear cleft, acute or chronic, with collection of fluid in the middle ear with an intact tympanic membrane. It is a very common disease in childhood, the most frequent cause of hearing loss in childhood and often requiring surgery. OME is called

Indexed as

AllergyInfancyInflammation; eosinophilic otititis mediaOMERhinosinusitisRisk factors

Identifiers

PMID29158869
PMCPMC5684754
OpenAlexW2756436602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.