Evidence map›Paper›PMID 29158844›Full record

ReviewTheranostics2017

Quantitative Imaging for Targeted Radionuclide Therapy Dosimetry - Technical Review.

Tiantian Li, Edwin C I Ao, Bieke Lambert, Boudewijn Brans, Stefaan Vandenberghe, Greta S P Mok

Open access · goldAbstract readReview
In one paragraph

Review in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 94 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Inter-institutional variability in kidney dosimetry duringRadiological physics and technology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Bias and precision of SPECT-basedEJNMMI physics · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Predicting [EJNMMI physics · 2023
    Article
  16. Radionuclide-based theranostics - a promising strategy for lung cancer.European journal of nuclear medicine and molecular imaging · 2023
    Review
  17. SPECT and CT misregistration reduction in [European journal of nuclear medicine and molecular imaging · 2023
    Article
  18. An Overview of In Vitro Assays ofDiagnostics (Basel, Switzerland) · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Tiantian LiBiomedical Imaging Laboratory, Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau SAR, China.
Edwin C I AoBiomedical Imaging Laboratory, Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau SAR, China.
Bieke LambertDept of Radiology and Nuclear medicine, Ghent University, De Pintelaan 185 9000 Gent, Belgium.
Boudewijn BransDept of Nuclear Medicine, UZ Ghent-Ghent University, St-Pietersnieuwstraat 41, 9000 Gent, Belgium.
Stefaan VandenbergheMEDISIP-ELIS-IBITECH-IMEC, Ghent University, St-Pietersnieuwstraat 41, 9000 Gent, Belgium.
Greta S P MokBiomedical Imaging Laboratory, Department of Electrical and Computer Engineering, Faculty of Science and Technology, University of Macau, Macau SAR, China.
University of Macau · MOGhent University · BEAZ Maria Middelares · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeted radionuclide therapy (TRT) is a promising technique for cancer therapy. However, in order to deliver the required dose to the tumor, minimize potential toxicity in normal organs, as well as monitor therapeutic effects, it is important to assess the individualized internal dosimetry based on patient-specific data. Advanced imaging techniques, especially radionuclide imaging, can be used to determine the spatial distribution of administered tracers for calculating the organ-absorbed dose. While planar scintigraphy is still the mainstream imaging method, SPECT, PET and bremsstrahlung imaging have promising properties to improve accuracy in quantification. This article reviews the basic principles of TRT and discusses the latest development in radionuclide imaging techniques for different theranostic agents, with emphasis on their potential to improve personalized TRT dosimetry.

Indexed as

HumansRadioimmunotherapyRadiometryRadionuclide ImagingRadiopharmaceuticalsTomography, Emission-Computed, Single-PhotonRadiopharmaceuticalsinternal dosimetryNuclear medicine imagingtargeted radionuclide therapytheranostic agents.

Identifiers

PMID29158844
PMCPMC5695148
OpenAlexW2766810683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.