Evidence map›Paper›PMID 29158835›Full record

ArticleTheranostics2017

Theranostic Role of

Mirco Galiè, Federico Boschi, Ilaria Scambi, Flavia Merigo, Pasquina Marzola, Luisa Altabella, Umberto Lavagnolo, Andrea Sbarbati, Antonello E Spinelli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mirco GalièDepartment of Neuroscience, Biomedicine and Movement, University of Verona, Piazzale L.A. Scuro 10, Verona 37134, Italy.
Federico BoschiDepartment of Computer Science, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.
Ilaria ScambiDepartment of Neuroscience, Biomedicine and Movement, University of Verona, Piazzale L.A. Scuro 10, Verona 37134, Italy.
Flavia MerigoDepartment of Neuroscience, Biomedicine and Movement, University of Verona, Piazzale L.A. Scuro 10, Verona 37134, Italy.
Pasquina MarzolaDepartment of Computer Science, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.
Luisa AltabellaMedical Physics Department, San Raffaele Scientific Institute, Via Olgettina 60, 20182 Milan, Italy.
Umberto LavagnoloDepartment of Neuroscience, Biomedicine and Movement, University of Verona, Piazzale L.A. Scuro 10, Verona 37134, Italy.
Andrea SbarbatiDepartment of Neuroscience, Biomedicine and Movement, University of Verona, Piazzale L.A. Scuro 10, Verona 37134, Italy.
Antonello E SpinelliExperimental Imaging Centre, San Raffaele Scientific Institute, Via Olgettina 60, 20182 Milan, Italy.
University of Verona · ITSan Raffaele University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug inaccessibility to vast areas of the tumor parenchyma is amongst the major hurdles for conventional therapies. Treatment efficacy rapidly decreases with distance from vessels and most of the tumor cells survive therapy. Also, between subsequent cycles of treatment, spared cancer cells replace those killed near the vessels, improving their access to nutrients, boosting their proliferation rate, and thus enabling tumor repopulation. Because of their property of "acting at a distance," radioisotopes are believed to overcome the physical barrier of vascular inaccessibility.

Indexed as

Adenosine TriphosphateAnimalsBeta ParticlesCell DeathCell Line, TumorHT29 CellsHumansLuminescenceMiceMice, NudeMolecular ImagingRadioisotopesRadiopharmaceuticalsTheranostic NanomedicineAdenosine TriphosphateRadioisotopesRadiopharmaceuticals32P-ATP radiopharmaceuticalCerenkov luminescence imagingcolorectal adenocarcinoma.magnetic resonance imaging

Identifiers

PMID29158835
PMCPMC5695139
OpenAlexW2766413030

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.