Evidence map›Paper›PMID 29158608›Full record

ArticleComputer methods in applied mechanics and engineering2017

A fully coupled space-time multiscale modeling framework for predicting tumor growth.

Mohammad Mamunur Rahman, Yusheng Feng, Thomas E Yankeelov, J Tinsley Oden

Abstract read
In one paragraph

Article in Computer methods in applied mechanics and engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Computational Modeling of Microwave Tumor Ablation.Bioengineering (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Estimating Glioblastoma Biophysical Growth Parameters Using Deep Learning Regression.Brainlesion : glioma, multiple sclerosis, stroke and traumatic brain injuries. BrainLes (Workshop) · 2021
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Coupling brain-tumor biophysical models and diffeomorphic image registration.Computer methods in applied mechanics and engineering · 2019
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammad Mamunur RahmanCenter for Simulation, Visualization and Real-Time Prediction, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, United States.
Yusheng FengCenter for Simulation, Visualization and Real-Time Prediction, The University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, United States.
Thomas E YankeelovCenter for Computational Oncology, The University of Texas at Austin, 201 East 24th St, Austin, TX 78712, United States.
J Tinsley OdenCenter for Computational Oncology, The University of Texas at Austin, 201 East 24th St, Austin, TX 78712, United States.

Funding

Quantitative Multiscale Imaging to Optimize Cancer Treatment StrategiesR01CA186193 · NCI · VANDERBILT UNIVERSITY · PI QUARANTA, VITO, RERICHA, ERIN C · 2014 to 2019
$3.1M
Image Driven Multi-Scale Modeling to Predict Treatment Response in Breast CancerU01CA174706 · NCI · VANDERBILT UNIVERSITY · PI QUARANTA, VITO, YANKEELOV, THOMAS E · 2013 to 2018
$2.5M
NCI NIH HHS R01 CA186193NCI NIH HHS U01 CA174706
6 · The paper itself

Abstract

Most biological systems encountered in living organisms involve highly complex heterogeneous multi-component structures that exhibit different physical, chemical, and biological behavior at different spatial and temporal scales. The development of predictive mathematical and computational models of multiscale events in such systems is a major challenge in contemporary computational biomechanics, particularly the development of models of growing tumors in humans. The aim of this study is to develop a general framework for tumor growth prediction by considering major biological events at tissue, cellular, and subcellular scales. The key to developing such multiscale models is how to bridge spatial and temporal scales that range from 10

Indexed as

Bridging scale algorithmCancer modelingContinuum mixture theoryNetwork modelingSignaling transduction pathwayTreatment outcome prediction

Identifiers

PMID29158608
PMCPMC5693401

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.