Evidence map›Paper›PMID 29158505›Full record

ArticleScientific reports2017

Dynamic profile of differentiated thyroid cancer in male and female patients with thyroidectomy during 2000-2013 in China: a retrospective study.

Hui-Xian Yan, Ping Pang, Fu-Lin Wang, Wen Tian, Yu-Kun Luo, Wei Huang, Guo-Qing Yang, Nan Jin, Li Zang, Jin Du and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  4. The challenges experienced by patients in the early period after thyroidectomy and the effects on sleep quality.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Hui-Xian YanDepartment of Endocrinology, Chinese PLA General Hospital, Beijing, 100853, China.
Ping PangDepartment of Endocrinology, Hainan Branch of PLA General Hospital, Sanya, 572013, Hainan, China.
Fu-Lin WangDepartment of Pathology, Chinese PLA General Hospital, Beijing, 100853, China.
Wen TianDepartment of General Surgery, Chinese PLA General Hospital, Beijing, 100853, China.
Yu-Kun LuoDepartment of Ultrasonography, Chinese PLA General Hospital, Beijing, 100853, China.
Wei HuangBeijing Haidian Hospital, Beijing Haidian Section of Peking University Third Hospital, Beijing, 100080, China.
Guo-Qing YangDepartment of Endocrinology, Chinese PLA General Hospital, Beijing, 100853, China.
Nan JinDepartment of Endocrinology, Chinese PLA General Hospital, Beijing, 100853, China.
Li ZangDepartment of Endocrinology, Chinese PLA General Hospital, Beijing, 100853, China.
Jin DuDepartment of Endocrinology, Chinese PLA General Hospital, Beijing, 100853, China.
Jian-Ming BaDepartment of Endocrinology, Chinese PLA General Hospital, Beijing, 100853, China.
Jing-Tao DouDepartment of Endocrinology, Chinese PLA General Hospital, Beijing, 100853, China.
Yi-Ming MuDepartment of Endocrinology, Chinese PLA General Hospital, Beijing, 100853, China.
Zhao-Hui LyuDepartment of Endocrinology, Chinese PLA General Hospital, Beijing, 100853, China. metabolism301@126.com.
Chinese PLA General Hospital · CNBeijing Haidian Hospital · CNHainan 301 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aimed to investigate the gender-related differences of disease onset, age distribution, blood type, clinical characteristics, and malignant behaviors of differentiated thyroid carcinoma (DTC) in Chinese patients. A total of 7385 consecutive thyroid cancer patients who underwent thyroidectomy were retrospectively reviewed. 4087 (55.3%) were diagnosed as benign and the other (3298, 44.7%) were as malignant. DTC accounted for 97.6% in the malignant tumor. More single nodules turned out to be DTC in male compared to multiple nodules (46.9% vs. 40.4%, P = 0.004). The proportion increased along with the increase of year during 2000-2013, which was from 7.5% to 68.1% in males and from 16.2% to 66.7% in females. The level of preoperative TSH was significantly higher in patients with DTC compared to the patients with benign (1.97 vs. 1.57 mIU/L, P < 0.001). The proportion of thyroid cancer was dominated in blood type B and the lowest incidence in blood type A in male, the difference was not statistically significant. The results showed that age, nodule number, BMI and serum TSH were the related factors for DTC. More aggressive behaviors of DTC were observed in male patients, and more attention should be focused on the timely diagnosis and treatment of these patients.

Indexed as

AdenocarcinomaAdultAgedAge FactorsBlood Grouping and CrossmatchingCarcinomaChinaFemaleHumansMaleMiddle AgedRetrospective StudiesSex CharacteristicsThyroidectomyThyroid NeoplasmsThyroid NoduleThyrotropin

Identifiers

PMID29158505
PMCPMC5696456
OpenAlexW2768781141

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.