Evidence map›Paper›PMID 29158443›Full record

ArticleDevelopment (Cambridge, England)2017

FOX and ETS family transcription factors regulate the pigment cell lineage in planarians.

Xinwen He, Nicole Lindsay-Mosher, Yan Li, Alyssa M Molinaro, Jason Pellettieri, Bret J Pearson

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Quantitative Analysis of Planarian Pigmentation.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  10. Review
  11. Review
  12. Frontiers in cell and developmental biology · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Xinwen HeHospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, Ontario M5G0A4, Canada.
Nicole Lindsay-MosherHospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, Ontario M5G0A4, Canada.
Yan LiHospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, Ontario M5G0A4, Canada.
Alyssa M MolinaroHospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, Ontario M5G0A4, Canada.
Jason PellettieriDepartment of Biology, Keene State College, Keene, NH 03435, USA.
Bret J PearsonHospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, Ontario M5G0A4, Canada bret.pearson@utoronto.ca.ORCID 0000-0002-3473-901X
University of Toronto · CAOntario Institute for Cancer Research · CAKeene State College · US

Funding

Cell Excretion: A Novel Mechanism of Apoptotic Cell ClearanceR15GM107826 · NIGMS · KEENE STATE COLLEGE · PI PELLETTIERI, JASON · 2014 to 2014
$307k
NIGMS NIH HHS R15 GM107826
6 · The paper itself

Abstract

Many pigment cells acquire unique structural properties and gene expression profiles during animal development. The underlying differentiation pathways have been well characterized in cells formed during embryogenesis, such as the neural crest-derived melanocyte. However, much less is known about the developmental origins of pigment cells produced in adult organisms during tissue homeostasis and repair. Here we report a lineage analysis of ommochrome- and porphyrin-producing cells in the brown, freshwater planarian

Indexed as

AnimalsBase SequenceCell DifferentiationCell LineageForkhead Transcription FactorsPhenothiazinesPigmentationPlanariansPorphyrinsProto-Oncogene Protein c-ets-1RegenerationRNA InterferenceRNA, Small InterferingSequence Analysis, RNAStem CellsTranscription, GeneticForkhead Transcription FactorsommochromePhenothiazinesPorphyrinsProto-Oncogene Protein c-ets-1RNA, Small InterferingPigment cellPlanarianRegenerationSchmidtea mediterranea

Identifiers

PMID29158443
PMCPMC5769623
OpenAlexW2770845723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.