Evidence map›Paper›PMID 29158426›Full record

ArticleGenetics2018

Cohesin Function in Cohesion, Condensation, and DNA Repair Is Regulated by Wpl1p via a Common Mechanism in

Michelle S Bloom, Douglas Koshland, Vincent Guacci

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Aberrant cohesin function inbioRxiv : the preprint server for biology · 2025
    Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michelle S BloomDepartment of Molecular and Cell Biology, University of California, Berkeley, California 94720.
Douglas KoshlandDepartment of Molecular and Cell Biology, University of California, Berkeley, California 94720 koshland@berkeley.edu.
Vincent GuacciDepartment of Molecular and Cell Biology, University of California, Berkeley, California 94720.
University of California, Berkeley · US

Funding

THE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4M
Elucidating chromosome structure and function through the lens of SMC complexes and R-loopsR35GM118189 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI KOSHLAND, DOUGLAS E · 2016 to 2025
$7.1M
NIGMS NIH HHS R35 GM118189NIGMS NIH HHS T32 GM007232
6 · The paper itself

Abstract

Cohesin tethers DNA to mediate sister chromatid cohesion, chromosome condensation, and DNA repair. How the cell regulates cohesin to perform these distinct functions remains to be elucidated. One cohesin regulator, Wpl1p, was characterized in

Indexed as

DNA RepairBinding SitesCell CycleCell Cycle ProteinsChromatidsChromosomal Proteins, Non-HistoneChromosomes, FungalCohesinsDNA DamageModels, BiologicalModels, MolecularProtein BindingProtein ConformationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTopoisomerase I InhibitorsCell Cycle ProteinsChromosomal Proteins, Non-HistoneCohesinsRAD61 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTopoisomerase I InhibitorscohesincondensationDNA repairsister chromatid cohesionWpl1

Identifiers

PMID29158426
PMCPMC5753852
OpenAlexW2768955566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.