Evidence map›Paper›PMID 29158418›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

A Novel

Wenting Huang, Daniel B Rainbow, Yuehong Wu, David Adams, Pranavkumar Shivakumar, Leah Kottyan, Rebekah Karns, Bruce Aronow, Jorge Bezerra, M Eric Gershwin and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Biliary Atresia Animal Models: Is the Needle in a Haystack?International journal of molecular sciences · 2022
    Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Wenting HuangDivision of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH 45267.
Daniel B RainbowJDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Center for Human Genetics, Nuffield Department of Medicine, National Institute for Health Research Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7BN, United Kingdom.
Yuehong WuDivision of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH 45267.
David AdamsDivision of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH 45267.
Pranavkumar ShivakumarDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.ORCID 0000-0002-2095-0623
Leah KottyanDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.ORCID 0000-0003-3979-2220
Rebekah KarnsDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
Bruce AronowDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.
Jorge BezerraDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229.ORCID 0000-0001-9667-7742
M Eric GershwinDivision of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, CA 95616; and.
Laurence B PetersonDepartment of Pharmacology, Merck Research Laboratories, Rahway, NJ 07065.
Linda S WickerJDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Center for Human Genetics, Nuffield Department of Medicine, National Institute for Health Research Oxford Biomedical Research Centre, University of Oxford, Oxford OX3 7BN, United Kingdom.ORCID 0000-0001-7771-0324
William M RidgwayDivision of Immunology, Allergy and Rheumatology, University of Cincinnati College of Medicine, Cincinnati, OH 45267; ridgwawm@ucmail.uc.edu.
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati Medical Center · USCentre for Human Genetics · GBMerck & Co., Inc., Rahway, NJ, USA (United States) · USUniversity of California, Davis · US

Funding

Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI James M Wells · 2007 to 2026
$24.4M
THE PATHOGENESIS OF AUTOIMMUNITY IN A MURINE MODEL OF PRIMARY BILIARY CIRRHOSISR01DK074768 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GERSHWIN, MERRILL E · 2006 to 2010
$2.8M
Mechanism of NOD.IDD3/10/17/18/9(LD) Liver DiseaseR01DK060714 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI RIDGWAY, WILLIAM M · 2002 to 2005
$911k
Immunogenetic Control of Autoimmune Liver DiseaseI01BX000827 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI RIDGWAY, WILLIAM M · 2012 to 2015
–
BLRD VA I01 BX000827BLRD VA I01 BX003821NIDDK NIH HHS P30 DK078392NIDDK NIH HHS R01 DK060714NIDDK NIH HHS R01 DK074768Wellcome Trust
6 · The paper itself

Abstract

We previously reported that NOD.c3c4 mice develop spontaneous autoimmune biliary disease (ABD) with anti-mitochondrial Abs, histopathological lesions, and autoimmune T lymphocytes similar to human primary biliary cholangitis. In this article, we demonstrate that ABD in NOD.c3c4 and related NOD ABD strains is caused by a chromosome 1 region that includes a novel mutation in polycystic kidney and hepatic disease 1 (

Indexed as

AnimalsAutoimmune DiseasesChimeraCholangitisDiabetes MellitusDisease Models, AnimalGenetic BackgroundHumansLiver Cirrhosis, BiliaryMiceMice, Inbred C57BLMice, Inbred NODMutationReceptors, Cell SurfaceTerminal Repeat SequencesPkhd1 protein, mouseReceptors, Cell Surface

Identifiers

PMID29158418
PMCPMC5757511
OpenAlexW2770612611

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.