Evidence map›Paper›PMID 29158400›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Belinda S Pinto, Terry L Orr-Weaver

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Meiosis I Kinase Regulators: Conserved Orchestrators of Reductional Chromosome Segregation.BioEssays : news and reviews in molecular, cellular and developmental biology · 2020
    Article
  8. Review
  9. Shugoshin protects centromere pairing and promotes segregation of nonexchange partner chromosomes in meiosis.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  10. Article
  11. Inhibition of Protein Phosphatase 2A Sensitizes Mucoepidermoid Carcinoma to Chemotherapy via the PI3K-AKT Pathway in Response to Insulin Stimulus.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Belinda S PintoWhitehead Institute for Biomedical Research, Cambridge, MA 02142.
Terry L Orr-WeaverWhitehead Institute for Biomedical Research, Cambridge, MA 02142; weaver@wi.mit.edu.
Whitehead Institute for Biomedical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proper segregation of chromosomes in meiosis is essential to prevent miscarriages and birth defects. This requires that sister chromatids maintain cohesion at the centromere as cohesion is released on the chromatid arms when the homologs segregate at anaphase I. The Shugoshin proteins preserve centromere cohesion by protecting the cohesin complex from cleavage, and this has been shown in yeasts to be mediated by recruitment of the protein phosphatase 2A B' (PP2A B'). In metazoans, delineation of the role of PP2A B' in meiosis has been hindered by its myriad of other essential roles. The

Indexed as

AnimalsCell Cycle ProteinsCentromereChromosome SegregationChromosomes, InsectDrosophila melanogasterDrosophila ProteinsMaleMeiosisNondisjunction, GeneticProtein Phosphatase 2Protein TransportSex ChromosomesCell Cycle ProteinsDrosophila Proteinsmei-S332 protein, DrosophilaProtein Phosphatase 2Wdb protein, DrosophilaWrd protein, Drosophilacentromerechromosome segregationmeiosissister-chromatid cohesionspermatogenesis

Identifiers

PMID29158400
PMCPMC5724294
OpenAlexW2771057255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.