ArticleHypertension (Dallas, Tex. : 1979)2018
Cerebrovascular Reactivity and Vascular Activation in Postmenopausal Women With Histories of Preeclampsia.
3 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph
Article in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
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20citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Shear Stress in the Cerebrovascular Response to Acute Exercise
Autonomic Dysfunction, Brain Blood Flow and Cognitive Decline in Veterans With Gulf War Illness
The Impact of Cerebral Anatomical Variations on Cerebrovascular Reactivity
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Reproducibility of cerebrovascular reactivity measurements: A systematic review of neuroimaging techniquesJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Pooled it
- Can exercise training enhance the repeated remote ischaemic preconditioning stimulus on peripheral and cerebrovascular function in high-risk individuals?European journal of applied physiology · 2021Trial
- Higher Levels of Cardiovascular Biomarkers Following Hypertensive Compared to Normotensive Pregnancy.Pregnancy (Hoboken, N.J.) · 2025Article
- Hypertensive disorders of pregnancy and neuroimaging markers of dementia risk: A pilot study.Pregnancy (Hoboken, N.J.) · 2025Article
- Sex differences in sleep apnea and Alzheimer's Disease: role of cerebrovascular dysfunction.npj women's health · 2025Review
- Maternal Microvascular Dysfunction During and After Preeclamptic Pregnancy.Comprehensive Physiology · 2024Review
- Characterising cerebrovascular reactivity and the pupillary light response-a comparative study.Frontiers in physiology · 2024Article
- Association between serum prostacyclin and cerebrovascular reactivity in healthy young and older adults.Experimental physiology · 2023Article
- Age at natural menopause impacts cerebrovascular reactivity and brain structure.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Article
- Effects of age and sex on middle cerebral artery blood velocity and flow pulsatility index across the adult lifespan.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Cognition and Cerebrovascular Reactivity in Midlife Women With History of Preeclampsia and Placental Evidence of Maternal Vascular Malperfusion.Frontiers in aging neuroscience · 2021Article
- Association of Ambient air Pollution with risk of preeclampsia during pregnancy: a retrospective cohort study.BMC public health · 2020Article
- Aortic Hemodynamics and Cognitive Performance in Postmenopausal Women: Impact of Pregnancy History.American journal of hypertension · 2020Article
- Risk factors of neurovascular ageing in women.Journal of neuroendocrinology · 2020Review
- Augmented cerebral blood velocity in response to isometric handgrip exercise in women with a history of preeclampsia.American journal of physiology. Regulatory, integrative and comparative physiology · 2019Article
- Pregnancy History, Hypertension, and Cognitive Impairment in Postmenopausal Women.Current hypertension reports · 2019Review
- Cerebral Blood Flow Regulation in Pregnancy, Hypertension, and Hypertensive Disorders of Pregnancy.Brain sciences · 2019Review
- Cardiovascular System in Preeclampsia and Beyond.Hypertension (Dallas, Tex. : 1979) · 2019Review
- Age-Related Reductions in Cerebrovascular Reactivity Using 4D Flow MRI.Frontiers in aging neuroscience · 2019Article
- Residual vascular dysfunction in women with a history of preeclampsia.American journal of physiology. Regulatory, integrative and comparative physiology · 2018Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Jill N BarnesFrom the Bruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison (J.N.B., K.B.M.); and Department of Anesthesiology (J.N.B., K.R.M., M.J.J.), College of Medicine and Science (R.E.H.), Department of Physiology and Biomedical Engineering (M.J., V.M.M.), Heath Science Research, Division of Epidemiology and Biostatistics (B.D.L., K.R.B.), and Department of Surgery (V.M.M.), Mayo Clinic, Rochester, MN. jnbarnes@wisc.edu.
Ronée E HarveyFrom the Bruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison (J.N.B., K.B.M.); and Department of Anesthesiology (J.N.B., K.R.M., M.J.J.), College of Medicine and Science (R.E.H.), Department of Physiology and Biomedical Engineering (M.J., V.M.M.), Heath Science Research, Division of Epidemiology and Biostatistics (B.D.L., K.R.B.), and Department of Surgery (V.M.M.), Mayo Clinic, Rochester, MN.
Kathleen B MillerFrom the Bruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison (J.N.B., K.B.M.); and Department of Anesthesiology (J.N.B., K.R.M., M.J.J.), College of Medicine and Science (R.E.H.), Department of Physiology and Biomedical Engineering (M.J., V.M.M.), Heath Science Research, Division of Epidemiology and Biostatistics (B.D.L., K.R.B.), and Department of Surgery (V.M.M.), Mayo Clinic, Rochester, MN.
Muthuvel JayachandranFrom the Bruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison (J.N.B., K.B.M.); and Department of Anesthesiology (J.N.B., K.R.M., M.J.J.), College of Medicine and Science (R.E.H.), Department of Physiology and Biomedical Engineering (M.J., V.M.M.), Heath Science Research, Division of Epidemiology and Biostatistics (B.D.L., K.R.B.), and Department of Surgery (V.M.M.), Mayo Clinic, Rochester, MN.
Katherine R MaltererFrom the Bruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison (J.N.B., K.B.M.); and Department of Anesthesiology (J.N.B., K.R.M., M.J.J.), College of Medicine and Science (R.E.H.), Department of Physiology and Biomedical Engineering (M.J., V.M.M.), Heath Science Research, Division of Epidemiology and Biostatistics (B.D.L., K.R.B.), and Department of Surgery (V.M.M.), Mayo Clinic, Rochester, MN.
Brian D LahrFrom the Bruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison (J.N.B., K.B.M.); and Department of Anesthesiology (J.N.B., K.R.M., M.J.J.), College of Medicine and Science (R.E.H.), Department of Physiology and Biomedical Engineering (M.J., V.M.M.), Heath Science Research, Division of Epidemiology and Biostatistics (B.D.L., K.R.B.), and Department of Surgery (V.M.M.), Mayo Clinic, Rochester, MN.
Kent R BaileyFrom the Bruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison (J.N.B., K.B.M.); and Department of Anesthesiology (J.N.B., K.R.M., M.J.J.), College of Medicine and Science (R.E.H.), Department of Physiology and Biomedical Engineering (M.J., V.M.M.), Heath Science Research, Division of Epidemiology and Biostatistics (B.D.L., K.R.B.), and Department of Surgery (V.M.M.), Mayo Clinic, Rochester, MN.
Michael J JoynerFrom the Bruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison (J.N.B., K.B.M.); and Department of Anesthesiology (J.N.B., K.R.M., M.J.J.), College of Medicine and Science (R.E.H.), Department of Physiology and Biomedical Engineering (M.J., V.M.M.), Heath Science Research, Division of Epidemiology and Biostatistics (B.D.L., K.R.B.), and Department of Surgery (V.M.M.), Mayo Clinic, Rochester, MN.
Virginia M MillerFrom the Bruno Balke Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin-Madison (J.N.B., K.B.M.); and Department of Anesthesiology (J.N.B., K.R.M., M.J.J.), College of Medicine and Science (R.E.H.), Department of Physiology and Biomedical Engineering (M.J., V.M.M.), Heath Science Research, Division of Epidemiology and Biostatistics (B.D.L., K.R.B.), and Department of Surgery (V.M.M.), Mayo Clinic, Rochester, MN.
University of Wisconsin–Madison · US
Funding
Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2MSex-specific Risk for Vascular Dysfunction and Cognitive DeclineP50AG044170 · NIA · MAYO CLINIC ROCHESTER · PI MILLER, VIRGINIA M · 2012 to 2017
$6.1MNeurovascular Control and Blood Pressure Regulation in HumansR01HL083947 · NHLBI · MAYO CLINIC ROCHESTER · PI JOYNER, MICHAEL J · 2007 to 2016
$3.6MCerebral blood flow, connectivity and cognition: the effect of age and exerciseR00HL118154 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BARNES, JILL NICOLE · 2015 to 2017
$735kCerebral blood flow, connectivity and cognition: the effect of age and exerciseK99HL118154 · NHLBI · MAYO CLINIC ROCHESTER · PI BARNES, JILL NICOLE · 2014 to 2015
$180kNCATS NIH HHS UL1 TR000135NHLBI NIH HHS K99 HL118154NHLBI NIH HHS R00 HL118154NHLBI NIH HHS R01 HL083947NIA NIH HHS P50 AG044170
Abstract
Cerebrovascular reactivity (CVR) is reduced in patients with cognitive decline. Women with a history of preeclampsia are at increased risk for cognitive decline. This study examined an association between pregnancy history and CVR using a subgroup of 40 age- and parity-matched pairs of women having histories of preeclampsia (n=27) or normotensive pregnancy (n=29) and the association of activated blood elements with CVR. Middle cerebral artery velocity was measured by Doppler ultrasound before and during hypercapnia to assess CVR. Thirty-eight parameters of blood cellular elements, microvesicles, and cell-cell interactions measured in venous blood were assessed for association with CVR using principal component analysis. Middle cerebral artery velocity was lower in the preeclampsia compared with the normotensive group at baseline (63±4 versus 73±3 cm/s;
Indexed as
Cognitive DysfunctionMiddle Cerebral ArteryPostmenopausePre-EclampsiaAdultBlood Flow VelocityBlood PressureCerebrovascular CirculationFemaleHumansMedical History TakingMiddle AgedPregnancyPrincipal Component AnalysisPrognosisRisk Factorshypercapniamiddle cerebral arterymonocytesplatelet aggregationpregnancy
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.