Evidence map›Paper›PMID 29158278›Full record

ArticleAntimicrobial agents and chemotherapy2018

Characterization of Plasmodium Atg3-Atg8 Interaction Inhibitors Identifies Novel Alternative Mechanisms of Action in Toxoplasma gondii.

Joseph M Varberg, Kaice A LaFavers, Gustavo Arrizabalaga, William J Sullivan

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  7. Modulation of autophagy as a therapeutic strategy forFrontiers in cellular and infection microbiology · 2022
    Review
  8. Review
  9. Binding Features and Functions of ATG3.Frontiers in cell and developmental biology · 2021
    Review
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Joseph M VarbergDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Kaice A LaFaversDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Gustavo Arrizabalaga *Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
William J Sullivan *Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA wjsulliv@iupui.edu.ORCID 0000-0003-1823-8642
Indiana University School of Medicine

Funding

Immunology and Infectious Diseases Training ProgramT32AI060519 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MARK H KAPLAN · 2004 to 2026
$6.0M
Calcium signaling in the parasitophorous vacuole of Toxoplasma gondiiR21AI119516 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI ARRIZABALAGA, GUSTAVO A · 2015 to 2016
$460k
Elucidating new and old roles for autophagy-like proteins in Toxoplasma gondiiR21AI125822 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI ARRIZABALAGA, GUSTAVO A, SULLIVAN, WILLIAM J · 2016 to 2017
$428k
NIAID NIH HHS R21 AI119516NIAID NIH HHS R21 AI125822NIAID NIH HHS T32 AI060519
6 · The paper itself

Abstract

Protozoan parasites, including the apicomplexan pathogens

Indexed as

Amino Acid SequenceAntiprotozoal AgentsAutophagyAutophagy-Related ProteinsBinding SitesDNA ReplicationFibroblastsGene ExpressionHumansLipid MetabolismMitochondriaMolecular Docking SimulationPlasmodium falciparumProtein BindingProtein Conformation, alpha-HelicalProtein Conformation, beta-StrandAntiprotozoal AgentsAutophagy-Related ProteinsProtein IsoformsProtozoan ProteinsSmall Molecule Librariesantiparasitic agentsapicomplexan parasitesautophagyparasitesPlasmodiumToxoplasma

Identifiers

PMID29158278
PMCPMC5786771
OpenAlexW2770067127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.