Evidence map›Paper›PMID 29158272›Full record

ArticleAntimicrobial agents and chemotherapy2018

Combination Antibiotic Exposure Selectively Alters the Development of Vancomycin Intermediate Resistance in Staphylococcus aureus.

Xuting Zheng, Andrew D Berti, Sue McCrone, Melanie Roch, Adriana E Rosato, Warren E Rose, Baiyi Chen

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
  7. Knockout ofJournal of bacteriology · 2022
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Methicillin-resistantInfection and drug resistance · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xuting ZhengDivision of Infectious Disease, The First Hospital of China Medical University, Shenyang, People's Republic of China.
Andrew D BertiSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Sue McCroneSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Melanie RochDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, Texas, USA.
Adriana E RosatoDepartment of Pathology and Genomic Medicine, Houston Methodist Research Institute, Houston, Texas, USA.
Warren E RoseSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin, USA warren.rose@wisc.edu chenbaiyi63@163.com.
Baiyi ChenDivision of Infectious Disease, The First Hospital of China Medical University, Shenyang, People's Republic of China warren.rose@wisc.edu chenbaiyi63@163.com.
University of Wisconsin–Madison · USFirst Hospital of China Medical University · CNHouston Methodist · US

Funding

Mechanisms and use of penicillin-binding protein inhibition to optimize cationic peptide anti-MRSA treatmentR01AI132627 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ROSE, WARREN E · 2017 to 2021
$2.1M
Molecular bases of DAP-resistance-mediated sensitization to beta-lactams in MRSAR56AI102503 · NIAID · METHODIST HOSPITAL RESEARCH INSTITUTE · PI ROSATO, ADRIANA E · 2014 to 2014
$300k
NIAID NIH HHS R01 AI132627NIAID NIH HHS R56 AI102503
6 · The paper itself

Abstract

Invasive methicillin-resistant

Indexed as

Anti-Bacterial Agentsbeta-LactamsDrug Therapy, CombinationHumansMicrobial Sensitivity TestsStaphylococcal InfectionsStaphylococcus aureusVancomycinVancomycin ResistanceAnti-Bacterial Agentsbeta-LactamsVancomycinantimicrobial combinationsglycopeptidesStaphylococcus aureusvancomycin resistance

Identifiers

PMID29158272
PMCPMC5786807
OpenAlexW2771033246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.