Observational studyThe British journal of general practice : the journal of the Royal College of General Practitioners2017
Variations in presentation, management, and patient outcomes of urinary tract infection: a prospective four-country primary care observational cohort study.
Observational study in The British journal of general practice : the journal of the Royal College of General Practitioners, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- Escherichia coli Resistance to Fluoroquinolones in Community-Acquired Uncomplicated Urinary Tract Infection in Women: a Systematic Review.Antimicrobial agents and chemotherapy · 2020Pooled it
- Validity of microscopy for diagnosing urinary tract infection in general practice - a systematic review.Scandinavian journal of primary health care · 2019Pooled it
- Self-reported acceptability and feasibility of a multimodal intervention to reduce antibiotic prescriptions for urinary tract infections in primary care: a process evaluation of the RedAres trial among general practitioners and medical practice assistants.BMC health services research · 2025Trial
- Trial
- Identification of clinical and urine biomarkers for uncomplicated urinary tract infection using machine learning algorithms.Scientific reports · 2019Trial
- Pharmacists' Management of Urinary Tract Infection Symptoms in Community Pharmacy: Counseling Practices and Attitudes Toward Antibiotic Therapy.Pharmacy (Basel, Switzerland) · 2026Article
- Women's experiences of the assessment and management of urinary tract infections during the COVID-19 pandemic: a qualitative analysis of free-text comments from a national survey in England.JAC-antimicrobial resistance · 2025Article
- Knowledge, attitudes, and practice around urinary tract infections of general practice assistants in the Netherlands: a cross-sectional internet survey.BMC primary care · 2025Article
- Towards individualised treatment of urinary tract infections.Communications medicine · 2025Article
- Article
- The 2023 Garrod Lecture: Antimicrobial use and stewardship in primary care: what works, and what next?The Journal of antimicrobial chemotherapy · 2025Article
- Comparing visual and automated urine dipstick analysis in a general practice population.Scandinavian journal of primary health care · 2025Article
- Article
- Anti-inflammatory drugs as potential antimicrobial agents: a review.Frontiers in pharmacology · 2025Review
- Urinary tract infections in women in Catalonia, Spain: a population-based observational cohort study in primary care.Frontiers in pharmacology · 2025Article
- Qualitative study on shared decision making in cystitis management in general practice.BJGP open · 2024Article
- Quality of Antibiotic Prescribing for Outpatient Cystitis in Adult Females.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024Article
- Resistance to first-line antibiotic therapy among patients with uncomplicated acute cystitis in Melbourne, Australia: prevalence, predictors and clinical impact.JAC-antimicrobial resistance · 2024Article
- Therapeutic strategies for uncomplicated cystitis in women.GMS infectious diseases · 2024Review
- Management of urinary tract infections in the community: a clinical audit and patient survey.BJGP open · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRegional variations in the presentation of uncomplicated urinary tract infection (UTI) and pathogen sensitivity to antibiotics have been cited as reasons to justify differences in how the infections are managed, which includes the prescription of broad-spectrum antibiotics.
aimTo describe presentation and management of UTI in primary care settings, and explore the association with patient recovery, taking microbiological findings and case mix into account. DESIGN AND
settingProspective observational study of females with symptoms of uncomplicated UTI presenting to primary care networks in England, Wales, the Netherlands, and Spain.
methodClinicians recorded history, symptom severity, management, and requested mid-stream urine culture. Participants recorded, in a diary, symptom severity each day for 14 days. Time to recovery was compared between patient characteristics and between countries using two-level Cox proportional hazards models, with patients nested within practices.
resultsIn total, 797 females attending primary care networks in England (
conclusionVariation in presentation and management of uncomplicated UTI at a country primary care network level is clinically unwarranted and highlights a lack of consensus concerning optimal symptom control and antibiotic prescribing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.