Evidence map›Paper›PMID 29157207›Full record

ArticleBMC psychiatry2017

An ethnographic study of the effects of cognitive symptoms in patients with major depressive disorder: the IMPACT study.

Bjarke Ebert, Kamilla Miskowiak, Morten Kloster, Jon Johansen, Cara Eckholm, Torbjörn Wærner, Mads Holme, Louise Meldgaard Bruun

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bjarke Ebert, H. Lundbeck A/S, Ottiliavej 9, 2500, Valby, Denmark. BJEB@Lundbeck.com.
Kamilla MiskowiakPsychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, København Ø, Denmark.
Morten KlosterReD Associates, Kronprinsessegade 20, DK-1306, København, Denmark.
Jon Johansen, H. Lundbeck A/S, Ottiliavej 9, 2500, Valby, Denmark.
Cara EckholmReD Associates, Kronprinsessegade 20, DK-1306, København, Denmark.
Torbjörn Wærner, H. Lundbeck A/S, Ottiliavej 9, 2500, Valby, Denmark.
Mads HolmeReD Associates, Kronprinsessegade 20, DK-1306, København, Denmark.
Louise Meldgaard BruunAarhus University Hospital, Skovagervej 2, 8240, Risskov, Denmark.
Lundbeck (Denmark) · DKAarhus University Hospital · DKCopenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe manifestation of major depressive disorder (MDD) may include cognitive symptoms that can precede the onset of MDD and persist beyond the resolution of acute depressive episodes. However, little is known about how cognitive symptoms are experienced by MDD patients and the people around them.

methodsIn this international (Brazil, Canada, China, France, and Germany) ethnographic study, we conducted semi-structured interviews and observations of remitted as well as symptomatic MDD patients (all patients self-reported being diagnosed by an HCP and self-reported being on an antidepressant) aged 18-60 years with self-reported cognitive symptoms (N = 34). In addition, participating depressed patients' close family or friends (N = 31) were interviewed. Separately recruited from depressed participants, work colleagues (N = 21) and healthcare providers (HCPs; N = 13) of depressed individuals were interviewed.

resultsKey insights were that: (1) patients were generally unaware that their cognitive symptoms were linked to their depression and, instead, attributed these symptoms to negative aspects of their person (e.g., age, separate disease, laziness, exhaustion); (2) cognitive symptoms in MDD appeared to negatively impact patients' social relationships and patients' ability to handle daily tasks at work and at home; (3) patients' cognitive symptoms also impacted relationships with family members and coworkers; (4) patients' cognitive symptoms increased stress and feelings of failure, which in turn seemed to worsen the cognitive symptoms, thereby creating a destructive cycle; and (5) although HCPs recommended that patients re-engage in everyday activities to help overcome their depression, cognitive symptoms seemed to impede such functional recovery.

conclusionsTaken together, these findings highlight a negative impact of patients' cognitive symptoms on their social functioning, work performance, and quality of life on the people close to them, and consequently on the degree of functional recovery after depression.

Indexed as

Activities of Daily LivingAdolescentAdultAntidepressive AgentsBrazilCanadaChinaCognitive DysfunctionCost of IllnessDiagnostic Self EvaluationEthnopsychologyFamilyFemaleFranceFriendsGermanyAntidepressive AgentsBrazilCanadaChinaCognitive symptomsFranceGermanyMajor depressive disorderQualitative study

Identifiers

PMID29157207
PMCPMC5697414
OpenAlexW2769155576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.