Evidence map›Paper›PMID 29157116›Full record

ArticleIslets2018

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction.

Danielle J Borg, Felicia Y T Yap, Sahar Keshvari, David G Simmons, Linda A Gallo, Amelia K Fotheringham, Aowen Zhuang, Robyn M Slattery, Sumaira Z Hasnain, Melinda T Coughlan and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Islets, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Danielle J Borga Glycation and Diabetes, Mater Research Institute , The University of Queensland, Translational Research Institute , Brisbane , Australia.
Felicia Y T Yapc Baker IDI Heart and Diabetes Institute , Melbourne , Australia.
Sahar Keshvarib Inflammatory Diseases Biology and Therapeutics , Mater Research Institute- The University of Queensland, Translational Research Institute , Brisbane , Australia.
David G Simmonse School of Biomedical Sciences, The University of Queensland , St Lucia , Australia.
Linda A Galloa Glycation and Diabetes, Mater Research Institute , The University of Queensland, Translational Research Institute , Brisbane , Australia.
Amelia K Fotheringhama Glycation and Diabetes, Mater Research Institute , The University of Queensland, Translational Research Institute , Brisbane , Australia.
Aowen Zhuanga Glycation and Diabetes, Mater Research Institute , The University of Queensland, Translational Research Institute , Brisbane , Australia.
Robyn M Slatteryd Department of Immunology , Central and Eastern Clinical School, AMREP Precinct, Monash University , Melbourne , Australia.
Sumaira Z Hasnainb Inflammatory Diseases Biology and Therapeutics , Mater Research Institute- The University of Queensland, Translational Research Institute , Brisbane , Australia.
Melinda T Coughlanc Baker IDI Heart and Diabetes Institute , Melbourne , Australia.
Phillip Kantharidisc Baker IDI Heart and Diabetes Institute , Melbourne , Australia.
Josephine M Forbesa Glycation and Diabetes, Mater Research Institute , The University of Queensland, Translational Research Institute , Brisbane , Australia.
Translational Research Institute · AUMonash University · AUUniversity of Queensland · AUBaker Heart and Diabetes Institute · AUMater Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The contribution of environmental factors to pancreatic islet damage in type 1 diabetes remains poorly understood. In this study, we crossed mice susceptible to type 1 diabetes, where parental male (CD8

Indexed as

DietLactationMaternal Nutritional Physiological PhenomenaPrenatal Exposure Delayed EffectsAnimalsAnimals, NewbornDiabetes Mellitus, Type 1FemaleGlycation End Products, AdvancedIslets of LangerhansMaleMiceMice, Inbred C57BLMice, Inbred NODMice, TransgenicPregnancyGlycation End Products, Advancedadvanced glycation end productsdietary interventioninsulininsulitisisletNOD8.3Type 1 diabetes

Identifiers

PMID29157116
PMCPMC5796486
OpenAlexW2769932083

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.