Evidence map›Paper›PMID 29156823›Full record

ArticleOncotarget2017

Differential activation of Fyn kinase distinguishes saturated and unsaturated fats in mouse macrophages.

Elena Tarabra, Ting-Wen An Lee, Victor A Zammit, Manu Vatish, Eijiro Yamada, Jeffrey E Pessin, Claire C Bastie

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Elena TarabraDepartment of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.
Ting-Wen An LeeDepartment of Pediatric Endocrinology, The Valley Hospital, Ridgewood, NJ, USA.
Victor A ZammitDivision of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK.
Manu VatishNuffield Department of Obstetrics & Gynaecology, University of Oxford, Oxford, UK.
Eijiro YamadaDepartment of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Japan.
Jeffrey E PessinDepartment of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.
Claire C BastieDepartment of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA.
Albert Einstein College of Medicine · USUniversity of Warwick · GBGunma University · JPUniversity of Oxford · GBValley Hospital · US

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7M
REGULATION OF THE INSULIN RECEPTOR KINASER01DK033823 · NIDDK · UNIVERSITY OF IOWA · PI KURLAND, IRWIN JACK, PESSIN, JEFFREY E. · 1986 to 2022
$6.7M
FYN SRC Kinase Regulation of Fatty Acid Oxidation and Insulin SensitivityR01DK081412 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BASTIE, CLAIRE C · 2010 to 2014
$1.8M
British Heart Foundation PG/08/087/25872Medical Research Council MR/J003360/1Medical Research Council MR/K012819/1NIDDK NIH HHS P30 DK020541NIDDK NIH HHS P30 DK026687NIDDK NIH HHS R01 DK033823NIDDK NIH HHS R01 DK081412
6 · The paper itself

Abstract

Diet-induced obesity is associated with increased adipose tissue activated macrophages. Yet, how macrophages integrate fatty acid (FA) signals remains unclear. We previously demonstrated that Fyn deficiency (

Indexed as

adipose tissuefatty acidsFyn kinasemacrophagesobesity

Identifiers

PMID29156823
PMCPMC5689713
OpenAlexW2728754925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.