Evidence map›Paper›PMID 29156787›Full record

ArticleOncotarget2017

Natural compound bavachalcone promotes the differentiation of endothelial progenitor cells and neovascularization through the RORα-erythropoietin-AMPK axis.

Shuang Ling, Rong-Zhen Ni, Yunyun Yuan, Yan-Qi Dang, Qian-Mei Zhou, Shuang Liang, Fujiang Guo, Wei Feng, Yuanyuan Chen, Katsumi Ikeda and 2 more

Abstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shuang LingInstitute of Interdisciplinary Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Rong-Zhen NiInstitute of Interdisciplinary Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yunyun YuanInstitute of Interdisciplinary Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yan-Qi DangInstitute of Interdisciplinary Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Qian-Mei ZhouInstitute of Interdisciplinary Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Shuang LiangEngineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Fujiang GuoSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wei FengSchool of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yuanyuan ChenInstitute of Interdisciplinary Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Katsumi IkedaSchool of Pharmacy and Pharmaceutical Sciences, Mukogawa Women's University, Nishinomiya, Japan.
Yukio YamoriInstitute for World Health Development, Mukogawa Women's University, Nishinomiya, Japan.
Jin-Wen XuInstitute of Interdisciplinary Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In cardiovascular diseases, endothelial function is impaired and the level of circulating endothelial progenitor cells (EPCs) is low. This study investigated whether the natural bioactive component bavachalcone (BavaC) induces the differentiation of EPCs and neovascularization

Indexed as

bavachlconeendothelial progenitor cellerythropoietinneovascularizationRORα

Identifiers

PMID29156787
PMCPMC5689677

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.