Evidence map›Paper›PMID 29156628›Full record

ArticleGenes2017

Çağdaş Göktaş, Hatice Yiğit, Mehmet İlyas Coşacak, Bünyamin Akgül

Open access · goldAbstract read
In one paragraph

Article in Genes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. The Expression Pattern of tRNA-Derived Small RNAs in AdultInternational journal of molecular sciences · 2023
    Article
  3. Genomewide mCells · 2022
    Article
  4. Article
  5. Review
  6. Noncoding RNAs in apoptosis: identification and function.Turkish journal of biology = Turk biyoloji dergisi · 2022
    Review
  7. Cytoplasmically localized tRNA-derived fragments inhibit translation inTurkish journal of biology = Turk biyoloji dergisi · 2022
    Article
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Çağdaş GöktaşDepartment of Molecular Biology and Genetics, İzmir Institute of Technology, Gülbahçeköyü, 35430 Urla İzmir, Turkey. cagdasgoktas@gmail.com.ORCID 0000-0001-8659-2235
Hatice YiğitDepartment of Molecular Biology and Genetics, İzmir Institute of Technology, Gülbahçeköyü, 35430 Urla İzmir, Turkey. hatice.yigit@gmail.com.
Mehmet İlyas CoşacakDepartment of Molecular Biology and Genetics, İzmir Institute of Technology, Gülbahçeköyü, 35430 Urla İzmir, Turkey. m.i.cosacak@gmail.com.ORCID 0000-0003-2978-3902
Bünyamin AkgülDepartment of Molecular Biology and Genetics, İzmir Institute of Technology, Gülbahçeköyü, 35430 Urla İzmir, Turkey. bunyaminakgul@iyte.edu.tr.ORCID 0000-0001-9877-9689
Izmir Institute of Technology · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies point to the existence of poorly characterized small regulatory RNAs generated from mRNAs, rRNAs and tRNAs. To explore the subcellular location of tRNA-derived small RNAs, 0-1 and 7-8 h Drosophila embryos were fractionated on sucrose density gradients. Analysis of 12,553,921 deep-sequencing reads from unfractionated and fractionated Drosophila embryos has revealed that tRFs, which are detected mainly from the 5'ends of tRNAs, co-sediment with the non-polysomal fractions. Interestingly, the expression levels of a subset of tRFs change temporally following the maternal-to-zygotic transition in embryos. We detected non-polysomal association of tRFs in S2 cells as well. Differential tRF expression pattern points to developmental significance at the organismal level. These results suggest that tRFs are associated primarily with the non-polysomal complexes in Drosophila embryos and S2 cells.

Indexed as

DrosophilapolysometRFtRNA

Identifiers

PMID29156628
PMCPMC5704246
OpenAlexW2770116199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.