Evidence map›Paper›PMID 29156619›Full record

Trial reportNutrients2017

Standard vs. Calorie-Dense Immune Nutrition in Haemodynamically Compromised Cardiac Patients: A Prospective Randomized Controlled Pilot Study.

Sergey Efremov, Vladimir Lomivorotov, Christian Stoppe, Anna Shilova, Vladimir Shmyrev, Michail Deryagin, Alexander Karaskov

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Early enteral nutrition in critically-ill patients.World journal of critical care medicine · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sergey EfremovDepartment of Anesthesiology and Intensive Care, E. Meshalkin National Medical Research Center, 630055 Novosibirsk, Russia. sergefremov@mail.ru.ORCID 0000-0001-5581-9169
Vladimir LomivorotovDepartment of Anesthesiology and Intensive Care, E. Meshalkin National Medical Research Center, 630055 Novosibirsk, Russia. vv_lomivorotov@meshalkin.ru.
Christian StoppeDepartment of Intensive Care Medicine, University Hospital, RWTH Aachen University, 52074 Aachen, Germany. christian.stoppe@gmail.com.
Anna ShilovaLaboratory Diagnostics Department, E. Meshalkin National Medical Research Center, 630055 Novosibirsk, Russia. a_shilova@meshalkin.ru.
Vladimir ShmyrevDepartment of Anesthesiology and Intensive Care, E. Meshalkin National Medical Research Center, 630055 Novosibirsk, Russia. v_shmyrev@meshalkin.ru.
Michail DeryaginDepartment of Anesthesiology and Intensive Care, E. Meshalkin National Medical Research Center, 630055 Novosibirsk, Russia. mderyagin@mail.ru.
Alexander KaraskovDepartment of Anesthesiology and Intensive Care, E. Meshalkin National Medical Research Center, 630055 Novosibirsk, Russia. mail@meshalkin.ru.
Meshalkin National Medical Research Center · RURWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of study was to test the hypothesis that early enteral nutrition (EN) with calorie-dense and protein rich enteral formula improves enteral energy and protein delivery in critically ill cardiac patients.

methodsProspective randomized pilot study of 40 ventilated adult patients undergoing elective cardiac surgery with use of cardiopulmonary bypass receiving inotropic support postoperatively. Patients were to receive either standard isocaloric (1000 Kcal/L and 38 g/L protein) early EN (

resultsThe mean time to EN initiation was 27 ± 11 h. Early EN with the calorie-dense formula provided significantly more energy and protein enteral delivery on the 2nd, (

conclusionPresent findings support hypothesis that early EN using a calorie-dense and protein rich formula leads to better enteral energy and protein delivery and higher levels of short-lived serum proteins.

Indexed as

Energy IntakeEnteral NutritionAgedBody Mass IndexCardiovascular DiseasesCritical IllnessDietary CarbohydratesDietary FatsDietary ProteinsFemaleFood, FormulatedHemodynamicsHumansMaleMicronutrientsMiddle AgedDietary CarbohydratesDietary FatsDietary ProteinsMicronutrientsPrealbuminTransferrincardiac surgerycritical careearly enteral nutritionenergy-dense formulaenteral energy deliveryprotein-rich formula

Identifiers

PMID29156619
PMCPMC5707736
OpenAlexW2770133848

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.