ArticleAmerican journal of epidemiology2018
Invited Commentary: Exposure Biomarkers Indicate More Than Just Exposure.
Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- Consequential (and inconsequential) environmental epidemiology.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Perfluorooctanoic acid serum concentrations and half-lives in a community exposed to contaminated drinking water in New York State.Journal of exposure science & environmental epidemiology · 2025Article
- Combined Exposure to Folate and Lead during Pregnancy and Autistic-Like Behaviors among Canadian Children from the MIREC Pregnancy and Birth Cohort.Environmental health perspectives · 2024Article
- Pregnancy-related hemodynamic biomarkers in relation to trimester-specific maternal per - and polyfluoroalkyl substances exposures and adverse birth outcomes.Environmental pollution (Barking, Essex : 1987) · 2023Article
- Understanding the dynamics of physiological changes, protein expression, and PFAS in wildlife.Environment international · 2022Review
- Associations of single and multiple per- and polyfluoroalkyl substance (PFAS) exposure with vitamin D biomarkers in African American women during pregnancy.Environmental research · 2021Article
- Effects of gestational exposures to chemical mixtures on birth weight using Bayesian factor analysis in the Health Outcome and Measures of Environment (HOME) Study.Environmental epidemiology (Philadelphia, Pa.) · 2021Article
- Identifying Risk Factors for Levels of Per- and Polyfluoroalkyl Substances (PFAS) in the Placenta in a High-Risk Pregnancy Cohort in North Carolina.Environmental science & technology · 2020Article
- RE: "INVITED COMMENTARY: EXPOSURE BIOMARKERS INDICATE MORE THAN JUST EXPOSURE".American journal of epidemiology · 2018Article
- Prenatal exposure to legacy PFAS and neurodevelopment in preschool-aged Canadian children: The MIREC cohort.Neurotoxicology and teratologyArticle
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomarkers of environmental exposures have notable strengths in integrating information across diverse sources and routes of exposure and providing a marker reflecting biological dose. However, the physiological determinants of biomarker toxicokinetics and measured levels may also affect or be affected by disease determinants and thus introduce confounding. In a study published in this issue of the Journal, Sagiv et al. (Am J Epidemiol. 2018;187(4):793-802) sought empirical evidence on the role of renal clearance in biasing the association between perfluoroalkyl compounds measured in plasma during pregnancy and infant birth weight. They found little empirical support for such bias. The risk of such bias is greater when the exposure and health outcome are assessed closely in time, when physiological differences are large relative to variability in environmental levels, and when the physiological determinant has diverse functions and implications. While empirical examination has value, the potential bias is difficult to measure and control when the underlying associations among exposure biomarker, health outcome, and physiological determinant are weak.
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