Evidence map›Paper›PMID 29155917›Full record

ArticleAmerican journal of epidemiology2018

Associations Between Divorce and Onset of Drug Abuse in a Swedish National Sample.

Alexis C Edwards, Sara Larsson Lönn, Jan Sundquist, Kenneth S Kendler, Kristina Sundquist

Abstract read
In one paragraph

Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Family Genetic-Risk Profiles Associated With Divorce.Clinical psychological science : a journal of the Association for Psychological Science · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Military service and risk of subsequent drug use disorders among Swedish men.Social psychiatry and psychiatric epidemiology · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexis C EdwardsVirginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia.
Sara Larsson LönnCenter for Primary Health Care Research, Lund University, Malmö, Sweden.
Jan SundquistCenter for Primary Health Care Research, Lund University, Malmö, Sweden.
Kenneth S KendlerVirginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia.
Kristina SundquistCenter for Primary Health Care Research, Lund University, Malmö, Sweden.

Funding

Genetic, Social, and Developmental Epidemiology of Drug Use DisordersR01DA030005 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENNETH SEEDMAN KENDLER, JAN O SUNDQUIST · 2010 to 2026
$7.6M
Genetic influences on developmental heterogeneity of alcohol use disorderK01AA021399 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI EDWARDS, ALEXIS C · 2012 to 2016
$707k
NIAAA NIH HHS K01 AA021399NIDA NIH HHS R01 DA030005
6 · The paper itself

Abstract

Rates of drug abuse are higher among divorced individuals than among those who are married, but it is not clear whether divorce itself is a risk factor for drug abuse or whether the observed association is confounded by other factors. We examined the association between divorce and onset of drug abuse in a population-based Swedish cohort born during 1965-1975 (n = 651,092) using Cox proportional hazards methods, with marital status as a time-varying covariate. Potential confounders (e.g., demographics, adolescent deviance, and family history of drug abuse) were included as covariates. Parallel analyses were conducted for widowhood and drug-abuse onset. In models with adjustments, divorce was associated with a substantial increase in risk of drug-abuse onset in both sexes (hazard ratios > 5). Co-relative analyses (among biological relatives) were consistent with a partially causal role of divorce on drug-abuse onset. Widowhood also increased risk of drug-abuse onset, although to a lesser extent. Divorce is a potent risk factor for onset of drug abuse, even after adjusting for deviant behavior in adolescence and family history of drug abuse. The somewhat less-pronounced association with widowhood, particularly among men, suggests that the magnitude of association between divorce and drug abuse may not be generalizable to the end of a relationship.

Indexed as

AdultDivorceFemaleHumansMaleRisk FactorsSex CharacteristicsSubstance-Related DisordersSwedenWidowhoodYoung Adult

Identifiers

PMID29155917
PMCPMC5928459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.