Evidence map›Paper›PMID 29155880›Full record

ArticlePloS one2017

Molecular characterization of novel mosquito-borne Rickettsia spp. from mosquitoes collected at the Demilitarized Zone of the Republic of Korea.

Alice N Maina, Terry A Klein, Heung-Chul Kim, Sung-Tae Chong, Yu Yang, Kristin Mullins, Ju Jiang, Heidi St John, Richard G Jarman, Jun Hang and 1 more

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. IDCases · 2025
    Article
  3. Discovery ofFrontiers in microbiology · 2022
    Article
  4. Article
  5. Characterization of a novel transitional groupInternational journal of systematic and evolutionary microbiology · 2021
    Article
  6. Observational
  7. Article
  8. Article
  9. Diagnosis of spotted fever groupEpidemiology and infection · 2019
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alice N MainaViral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America.ORCID http://orcid.org/0000-0002-0248-8463
Terry A Klein65th Medical Brigade, Medical Department Activity-Korea, Unit 15281, Seoul, South Korea.
Heung-Chul Kim65th Medical Brigade, Medical Department Activity-Korea, Unit 15247, Seoul, South Korea.
Sung-Tae Chong65th Medical Brigade, Medical Department Activity-Korea, Unit 15247, Seoul, South Korea.
Yu YangViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Kristin MullinsViral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America.
Ju JiangViral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America.
Heidi St JohnViral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America.
Richard G JarmanViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Jun HangViral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Allen L RichardsViral and Rickettsial Diseases Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rickettsiae are associated with a diverse range of invertebrate hosts. Of these, mosquitoes could emerge as one of the most important vectors because of their ability to transmit significant numbers of pathogens and parasites throughout the world. Recent studies have implicated Anopheles gambiae as a potential vector of Rickettsia felis. Herein we report that a metagenome sequencing study identified rickettsial sequence reads in culicine mosquitoes from the Republic of Korea. The detected rickettsiae were characterized by a genus-specific quantitative real-time PCR assay and sequencing of rrs, gltA, 17kDa, ompB, and sca4 genes. Three novel rickettsial genotypes were detected (Rickettsia sp. A12.2646, Rickettsia sp. A12.2638 and Rickettsia sp. A12.3271), from Mansonia uniformis, Culex pipiens, and Aedes esoensis, respectively. The results underscore the need to determine the Rickettsia species diversity associated with mosquitoes, their evolution, distribution and pathogenic potential.

Indexed as

Genes, BacterialPhylogenyAedesAnimalsCulexGenotypeMetagenomeMosquito VectorsReal-Time Polymerase Chain ReactionRepublic of KoreaRickettsia

Identifiers

PMID29155880
PMCPMC5695765

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.