ArticlePloS one2017
Morphological characteristics of diffuse idiopathic skeletal hyperostosis in the cervical spine.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 37 citations in OpenAlex.
- Clinical Image: Esophageal Compression Secondary to Diffuse Idiopathic Skeletal Hyperostosis.Cureus · 2026Article
- Association of Arterial Hypertension with Thoracic Spondylophyte Formation: A Secondary Analysis of Cross-Sectional MRI Data from the SHIP Cohort.Healthcare (Basel, Switzerland) · 2026Article
- A rare presentation of diffuse idiopathic skeletal hyperostosis with progressive dysphagia and choking.Surgical neurology international · 2025Article
- Acute upper airway obstruction caused by cervical osteophytes in diffuse idiopathic skeletal hyperostosis: A case report.International journal of surgery case reports · 2024Article
- Cervical spine fracture in diffuse idiopathic skeletal hyperostosis: A bibliometric analysis.SAGE open medicine · 2024Article
- Imaging Characteristics of Diffuse Idiopathic Skeletal Hyperostosis: More Than Just Spinal Bony Bridges.Diagnostics (Basel, Switzerland) · 2023Review
- Surgical Treatment of Diffuse Idiopathic Skeletal Hyperostosis (DISH) Involving the Cervical Spine: Technical Nuances and Outcome of a Multicenter Experience.Global spine journal · 2022Article
- Diffuse Idiopathic Skeletal Hyperostosis of Cervical Spine with Dysphagia-Molecular and Clinical Aspects.International journal of molecular sciences · 2021Review
- Fusion for subaxial bow hunter's syndrome results in remote osseous remodeling of the hyperostotic growth responsible for vertebral artery compression.Surgical neurology international · 2021Article
- A Comparison of Cervical and Thoracolumbar Fractures Associated with Diffuse Idiopathic Skeletal Hyperostosis-A Nationwide Multicenter Study.Journal of clinical medicine · 2020Article
- Management of Airway Obstruction due to Diffuse Idiopathic Skeletal Hyperostosis in the Cervical Spine: A Case Report and Literature Review.Internal medicine (Tokyo, Japan) · 2019Review
- Cervical Spinal Fracture in a Patient with Diffuse Idiopathic Skeletal Hyperostosis Having a History of Cervical Laminoplasty.Asian journal of neurosurgeryArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDiffuse idiopathic skeletal hyperostosis (DISH) is characterized by anterior ossification of the spine and can lead to dysphagia and airway obstruction. The morphology of the newly formed bone in the cervical spine is different compared to the thoracic spine, possibly due to dissimilarities in local vascular anatomy. In this study the spatial relationship of the new bone with the arterial system, trachea and esophagus was analyzed and compared between subjects with and without DISH.
methodsCervical computed tomography (CT) scans were obtained from five patients with dysphagia and DISH and ten control subjects. The location of the vertebral and carotid arteries, surface area of the hyperostosis and distance between the vertebral body and the trachea and esophagus was assessed in the axial view.
resultsThe surface area of the newly formed bone was located symmetrically anterior to the vertebral body. The ossifications were non-flowing in the sagittal view and no segmental vessels were observed. Substantial displacement of the trachea/esophagus was present in the group with DISH compared to the controls.
conclusionsThe hyperostosis at the cervical level was symmetrically distributed anterior to the vertebral bodies without a flowing pattern, in contrast to the asymmetrical flowing pattern typically found in the thoracic spine. The hypothesis that the vascular system acts as a natural barrier against new bone formation in DISH could be further supported with these findings. The significant ventral displacement of the trachea and esophagus may explain the mechanism of dysphagia and airway obstruction in DISH.
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