Evidence map›Paper›PMID 29155835›Full record

ArticlePloS one2017

Assessment of transposition of the great arteries associated with multiple malformations using dual-source computed tomography.

Lin-Jun Xie, Li Jiang, Zhi-Gang Yang, Ke Shi, Hua-Yan Xu, Rui Li, Kai-Yue Diao, Ying-Kun Guo

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Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lin-Jun XieDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Li JiangDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Zhi-Gang YangDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0001-9341-7697
Ke ShiDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Hua-Yan XuDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Rui LiDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Kai-Yue DiaoDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Ying-Kun GuoDepartment of Radiology, Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the value of dual-source computed tomography (DSCT) in depicting the morphological characteristics and diagnosing the associated malformations for patients with transposition of the great arteries (TGA) before surgery. MATERIALS AND

methodsTwenty-five patients with TGA who underwent DSCT and transthoracic echocardiography (TTE) examination were retrospectively reviewed. The morphological types of TGA, the spatial relationship between the pulmonary artery and the aorta, as well as coronary artery-associated abnormalities were assessed by DSCT. In contrast to TTE, the diagnostic accuracy of associated malformations on DSCT were analyzed and calculated with reference to surgical or digital subtraction angiography (DSA) findings. Effective doses (EDs) were also calculated.

resultsAmong the 25 patients, 12 (48%) had ventricular septal defects and left ventricular outflow tract stenosis. Sixteen patients (16/25, 64%) had great arteries with an oblique spatial relationship on DSCT. In addition, we found seven patients (7/25, 28%) with coronary artery malformation, including five with an abnormal coronary origin and two with signs of a myocardial bridge. According to DSA or surgical findings, DSCT was superior to TTE in demonstrating extracardiac anomalies (sensitivity, anomalies of great vessels: 100% vs. 93.33%, other anomalies: 100% vs. 46.15%). The mean estimated ED for those aged <10 years was <2 mSv (1.59 ± 0.95 mSv).

conclusionsDSCT can achieve an overall assessment of patients with TGA, including any associated malformations as well as the identification of the spatial relationship of the great arteries. DSCT can therefore be considered as an alternative imaging modality for surgical decision making.

Indexed as

Computed Tomography AngiographyAdolescentAdultAortaChildChild, PreschoolCoronary AngiographyCoronary StenosisEchocardiographyFemaleHeart Defects, CongenitalHeart Septal Defects, VentricularHeart VentriclesHumansInfantMale

Identifiers

PMID29155835
PMCPMC5695805

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.