Evidence map›Paper›PMID 29155388›Full record

ReviewIET nanobiotechnology2017

Polyelectrolyte multilayers for bio-applications: recent advancements.

Suman Pahal, Ruchi Gakhar, Ashok M Raichur, Manoj M Varma

Abstract readReview
In one paragraph

Review in IET nanobiotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suman PahalCentre for Nano Science and Engineering, Indian Institute of Science, Bangalore 560012, India.
Ruchi GakharDepartment of Engineering Physics, University of Wisconsin, Madison, WI 53706, USA.
Ashok M RaichurNanotechnology and Water Sustainability Unit, University of South Africa, Florida 1710, Johannesburg, South Africa.
Manoj M VarmaCentre for Nano Science and Engineering, Indian Institute of Science, Bangalore 560012, India. mvarma@cense.iisc.ernet.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synergistic relationship between structure and the bulk properties of polyelectrolyte multilayer (PEM) films has generated tremendous interest in their application for loading and release of bioactive species. Layer-by-layer assembly is the simplest, cost effective process for fabrication of such PEMs films, leading to one of the most widely accepted platforms for incorporating biological molecules with nanometre precision. The bulk reservoir properties of PEM films render them a potential candidate for applications such as biosensing, drug delivery and tissue engineering. Various biomolecules such as proteins, DNA, RNA or other desired molecules can be incorporated into the PEM stack via electrostatic interactions and various other secondary interactions such as hydrophobic interactions. The location and availability of the biological molecules within the PEM stack mediates its applicability in various fields of biomedical engineering such as programmed drug delivery. The development of advanced technologies for biomedical applications using PEM films has seen rapid progress recently. This review briefly summarises the recent successes of PEM being utilised for diverse bio-applications.

Indexed as

Biosensing TechniquesDrug Delivery SystemsHydrophobic and Hydrophilic InteractionsNucleic AcidsPolyelectrolytesProteinsTissue EngineeringNucleic AcidsPolyelectrolytesProteins

Identifiers

PMID29155388
PMCPMC8676474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.