Observational studyJournal of pain and symptom management2018
Factors Associated With Attrition in a Multicenter Longitudinal Observational Study of Patients With Advanced Cancer.
Observational study in Journal of pain and symptom management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Impact of a complex intervention in primary care for patients with palliative care needs in their healthcare utilization: a before-after study.Primary health care research & development · 2026Trial
- Feasibility and effectiveness of a two-tiered intervention involving training and a new consultation model for patients with palliative care needs in primary care: A before-after study.Palliative medicine · 2024Trial
- A Multimodal Lifestyle Psychosocial Survivorship Program in Young Cancer Survivors: The CARE for CAYA Program-A Randomized Clinical Trial Embedded in a Longitudinal Cohort Study.JAMA network open · 2024Trial
- Characteristics and patient-reported outcomes associated with dropout in severely affected oncological patients: an exploratory study.BMC medical research methodology · 2021Trial
- Satisfaction with treatment decision-making and long-term experiences of life-prolonging treatments for metastatic castration-resistant prostate cancer.BMC palliative care · 2026Observational
- Exploring the anxiety, depression and perceived burden in advanced cancer: A longitudinal view on patients and caregivers.Palliative & supportive care · 2025Article
- Caregiver perception of quality of dying of cancer patients is associated with patient-reported quality of life during the last month of life.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Feasibility, Acceptability, and Potential Effects of a Digital Oral Anticancer Agent Intervention: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2025Article
- Symptom burden among men treated for castration-resistant prostate cancer: a longitudinal study.BMJ supportive & palliative care · 2024Article
- The effect of social care nurses on health related quality of life in patients with advanced cancer: A non-randomized, multicenter, controlled trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- An exploratory study of a multi-species probiotic formulation and markers of health in a real-world oncological cohort in the time of covid.Inflammopharmacology · 2024Article
- Head and neck cancer patients with geriatric deficits are more often non-responders and lost from follow-up in quality of life studies.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Attrition in the First Three Therapy Lines in Patients with Advanced Breast Cancer in the German Real-World PRAEGNANT Registry.Geburtshilfe und Frauenheilkunde · 2024Article
- Feasibility of a Health Coach Intervention to Reduce Sitting Time and Improve Physical Functioning Among Breast Cancer Survivors: Pilot Intervention Study.JMIR cancer · 2023Article
- Review of psychological interventions in patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Review
- Study retention and attrition in a longitudinal cohort study including patient-reported outcomes, fieldwork and biobank samples: results of the Netherlands quality of life and Biomedical cohort study (NET-QUBIC) among 739 head and neck cancer patients and 262 informal caregivers.BMC medical research methodology · 2022Article
- Continuous care needs in patients with cancer receiving chemotherapy during the recent omicron wave of COVID-19 in Shanghai: A qualitative study.Frontiers in psychology · 2022Article
- Epidemiology of Pain Among Patients with Solid Metastatic Cancer During the Last Year of Life.Journal of pain research · 2022Article
- Interim Analysis of Attrition Rates in Palliative Care Study on Dignity Therapy.The American journal of hospice & palliative care · 2021Article
- Correlates related to follow-up in a community engagement program in North Central Florida.Journal of community psychology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
contextAttrition is common in longitudinal observational studies in palliative care. Few studies have examined predictors of attrition.
objectivesTo identify patient characteristics at enrollment associated with attrition in palliative oncology outpatient setting.
methodsIn this longitudinal observational study, advanced cancer patients enrolled in an outpatient multicenter study were assessed at baseline and two to five weeks later. We compared baseline characteristics between patients who returned for follow-up and those who dropped out.
resultsSeven hundred forty-four patients were enrolled from Jordan, Brazil, Chile, Korea, and India. Attrition rate was 33%, with variation among countries (22%-39%; P = 0.023). In univariate analysis, baseline predictors for attrition were cognitive failure (odds ratio [OR] 1.23 per point in Memorial Delirium Assessment Scale; P < 0.01), functional status (OR 1.55 per 10-point decrease in Karnofsky Performance Status; P < 0.01), Edmonton Symptom Assessment Scale [ESAS] physical score (OR 1.03 per point; P < 0.01), ESAS emotional score (OR 1.05 per point; P < 0.01), and shorter duration between cancer diagnosis and palliative care referral in months (OR 0.89 per log; P = 0.028). In multivariate analysis, cognitive failure (OR 1.12 per point; P = 0.007), ESAS physical score (OR 1.18 per point; P = 0.027), functional status (OR 1.35 per 10-point decrease; P < 0.001), and shorter duration from cancer diagnosis (OR 0.86 per log; P = 0.01) remained independent predictors of attrition.
conclusionAdvanced cancer patients with cognitive failure, increased physical symptoms, poorer performance status, and shorter duration from cancer diagnosis were more likely to dropout. These results have implications for research design, patient selection, and data interpretation in longitudinal observational studies.
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