Evidence map›Paper›PMID 29154970›Full record

Trial reportChest2018

Patient Engagement Using New Technology to Improve Adherence to Positive Airway Pressure Therapy: A Retrospective Analysis.

Atul Malhotra, Maureen E Crocker, Leslee Willes, Colleen Kelly, Sue Lynch, Adam V Benjafield

Abstract readClinical TrialComparative StudyMulticenter Study
In one paragraph

Trial report in Chest, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Effect of Patient-Facing Applications on Positive Airway Pressure Therapy Adherence: A Systematic Review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019
    Pooled it
  3. Trial
  4. Impact of patient and family engagement in improving continuous positive airway pressure adherence in patients with obstructive sleep apnea: a randomized controlled trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Trial
  5. Effects of solriamfetol in a long-term trial of participants with obstructive sleep apnea who are adherent or nonadherent to airway therapy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Trial
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
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  14. Article
  15. Review
  16. Review
  17. Article
  18. Digital health delivery in respiratory medicine: adjunct, replacement or cause for division?European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  19. Continuous positive airway pressure is here to stay.The Lancet. Respiratory medicine · 2024
    Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Atul MalhotraDivision of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, La Jolla, CA. Electronic address: amalhotra@ucsd.edu.
Maureen E CrockerResMed Science Center, ResMed Corp, San Diego, CA.
Leslee WillesWilles Consulting Group, Encinitas, CA.
Colleen KellyKelly Statistical Consulting, San Diego, CA.
Sue LynchResMed Science Center, ResMed Corp, San Diego, CA.
Adam V BenjafieldResMed Science Center, ResMed Corp, San Diego, CA.

Funding

Neural Plasticity During Acclimatization to HypoxiaR01HL081823 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI POWELL, FRANK L. · 2005 to 2019
$4.5M
Single Motor Unit Genioglossus Recordings to Understand Sleep Apnea PathogenesisR01HL085188 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2008 to 2018
$3.5M
Imaging Blood Flow, Ventilation, and Density InteractionsR01HL119201 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOPKINS, SUSAN R · 2016 to 2019
$2.5M
Training in the Next Generation in Respiratory ScienceT32HL134632 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, POWELL, FRANK L. · 2017 to 2021
$2.1M
Assessment of Upper Airway Mechanics Using Newer Electromyographic TechniquesK24HL132105 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2016 to 2020
$611k
MR Imaging of Upper Airway Dynamics in Obstructive Sleep ApneaR21HL121794 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DARQUENNE, CHANTAL · 2014 to 2015
$423k
NHLBI NIH HHS K24 HL132105NHLBI NIH HHS R01 HL081823NHLBI NIH HHS R01 HL085188NHLBI NIH HHS R01 HL119201NHLBI NIH HHS R21 HL121794NHLBI NIH HHS T32 HL134632
6 · The paper itself

Abstract

backgroundSleep apnea has major neurocognitive and cardiovascular and metabolic risks. Treatment of sleep apnea is suboptimal because of variable adherence to existing therapies.

methodsThis trial compared positive airway pressure adherence among patients who were provided active patient engagement (APE) technology vs those who received usual care monitoring (UCM). The primary outcome was expressed by using the US Medicare definition of adherence. Adherence data from two cloud-based databases (AirView and myAir) were analyzed for patients with sleep apnea. Data were included if a patient's activation date in the APE tool was within 7 days of the therapy start date in the UCM database during a defined time window. Data were propensity matched in a 1:2 ratio (APE:UCM) based on baseline patient characteristics.

resultsA total of 128,037 patients were analyzed. Baseline characteristics were typical of a sleep clinic cohort. APE was associated with more patients achieving adherence criteria (87.3%) compared with UCM patients (70.4%; P < .0001 for the difference). Average therapy usage was 5.9 h per night in the APE group vs 4.9 h per night in the matched UCM patients (P < .0001). Patients with sleep apnea "struggling" with therapy adherence had a 17.6% absolute improvement in adherence using APE compared with UCM.

conclusionsRobust therapy adherence rates can be achieved by adding modern technology to usual care. Adopting advances in technology in care management may allow clinicians to more effectively and efficiently treat patients who have sleep apnea. Rigorous randomized controlled trials may be required before making strong clinical recommendations.

Indexed as

Continuous Positive Airway PressurePatient ComplianceBiomedical TechnologyHumansMiddle AgedPatient ParticipationRetrospective StudiesSleep Apnea, ObstructiveTreatment OutcomeCPAPlungOSAsleep-disordered breathingsleep medicine

Identifiers

PMID29154970
PMCPMC5989636

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.