Evidence map›Paper›PMID 29154958›Full record

ArticleThe Journal of allergy and clinical immunology2018

Pathogenic T

Karim H Shalaby, Miranda R Lyons-Cohen, Gregory S Whitehead, Seddon Y Thomas, Immo Prinz, Hideki Nakano, Donald N Cook

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. CD11bNature communications · 2021
    Article
  4. Article
  5. Article
  6. Indoor dust acts as an adjuvant to promote sensitization to peanut through the airway.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Karim H ShalabyImmunogenetics Group, Immunity, Inflammation and Disease Laboratory, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
Miranda R Lyons-CohenImmunogenetics Group, Immunity, Inflammation and Disease Laboratory, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
Gregory S WhiteheadImmunogenetics Group, Immunity, Inflammation and Disease Laboratory, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
Seddon Y ThomasImmunogenetics Group, Immunity, Inflammation and Disease Laboratory, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
Immo PrinzInstitut für Immunologie, Medizinische Hochschule, Hannover, Germany.
Hideki NakanoImmunogenetics Group, Immunity, Inflammation and Disease Laboratory, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC.
Donald N CookImmunogenetics Group, Immunity, Inflammation and Disease Laboratory, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC. Electronic address: cookd@niehs.nih.gov.
National Institute of Environmental Health Sciences · USNational Institutes of Health · USMedizinische Hochschule Hannover · DE

Funding

Allergic sensitization through the airwayZIAES102025 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI COOK, DONALD N · 2009 to 2025
$32.6M
genetic requirements of allergic responses in the lungZ01ES102025 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI COOK, DONALD N · 2006 to 2008
$3.4M
Intramural NIH HHS Z01 ES102025Intramural NIH HHS ZIA ES102025NULL ZIA ES102025-09
6 · The paper itself

Abstract

backgroundMechanisms that elicit mucosal T

objectiveWe sought to understand whether maintenance of lung T

methodsAnimals were exposed repeatedly to aspiration of ovalbumin alone or together with environmental adjuvants, including common house dust extract (HDE), to test their role in maintaining lung inflammation. Alternatively, antigen-specific effector/memory T

resultsT

conclusionT

Indexed as

AllergensAnimalsAspergillus oryzaeDendritic CellsDustEndotoxinsInflammationLungMice, Inbred C57BLMice, TransgenicOvalbuminTh17 CellsToll-Like Receptor 4AllergensDustEndotoxinsOvalbuminTlr4 protein, mouseToll-Like Receptor 4chronic inflammationdendritic cellshouse dust extractT(H)17 cellsToll-like receptor 4

Identifiers

PMID29154958
PMCPMC5951733
OpenAlexW2768621777

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.