Evidence map›Paper›PMID 29154948›Full record

ArticleBiochimica et biophysica acta. Molecular cell research2018

The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis.

Isotta Lorenzi, Silke Oeljeklaus, Abhishek Aich, Christin Ronsör, Sylvie Callegari, Jan Dudek, Bettina Warscheid, Sven Dennerlein, Peter Rehling

Open access · hybridAbstract read
In one paragraph

Article in Biochimica et biophysica acta. Molecular cell research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

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  14. Mitochondrial Structure and Bioenergetics in Normal and Disease Conditions.International journal of molecular sciences · 2021
    Review
  15. Review
  16. Functions of CytochromeInternational journal of molecular sciences · 2020
    Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Isotta LorenziDepartment of Cellular Biochemistry, University Medical Centre Göttingen, GZMB, D-37073 Göttingen, Germany.
Silke OeljeklausFaculty of Biology, Department of Biochemistry and Functional Proteomics, University Freiburg, D-79104 Freiburg, Germany; BIOSS Centre for Biological Signalling Studies, University of Freiburg, D-79104 Freiburg, Germany.
Abhishek AichDepartment of Cellular Biochemistry, University Medical Centre Göttingen, GZMB, D-37073 Göttingen, Germany.
Christin RonsörDepartment of Cellular Biochemistry, University Medical Centre Göttingen, GZMB, D-37073 Göttingen, Germany.
Sylvie CallegariDepartment of Cellular Biochemistry, University Medical Centre Göttingen, GZMB, D-37073 Göttingen, Germany.
Jan DudekDepartment of Cellular Biochemistry, University Medical Centre Göttingen, GZMB, D-37073 Göttingen, Germany.
Bettina WarscheidFaculty of Biology, Department of Biochemistry and Functional Proteomics, University Freiburg, D-79104 Freiburg, Germany; BIOSS Centre for Biological Signalling Studies, University of Freiburg, D-79104 Freiburg, Germany.
Sven DennerleinDepartment of Cellular Biochemistry, University Medical Centre Göttingen, GZMB, D-37073 Göttingen, Germany. Electronic address: Sven.Dennerlein@med.uni-goettingen.de.
Peter RehlingDepartment of Cellular Biochemistry, University Medical Centre Göttingen, GZMB, D-37073 Göttingen, Germany; Max Planck Institute for Biophysical Chemistry, D-37077 Göttingen, Germany. Electronic address: Peter.Rehling@medizin.uni-goettingen.de.
University of Göttingen · DEUniversity of Freiburg · DE

Funding

European Research Council 339580European Research Council 648235
6 · The paper itself

Abstract

The three mitochondrial-encoded proteins, COX1, COX2, and COX3, form the core of the cytochrome c oxidase. Upon synthesis, COX2 engages with COX20 in the inner mitochondrial membrane, a scaffold protein that recruits metallochaperones for copper delivery to the Cu

Indexed as

Electron Transport Complex IVHEK293 CellsHumansMembrane ProteinsMitochondrial MembranesMitochondrial ProteinsCOX20 protein, humanElectron Transport Complex IVMembrane ProteinsMitochondrial ProteinsCOX20 chaperoneCOX2 biogenesisCOX assemblyMitochondriaOxidative phosphorylationRespiratory chain

Identifiers

PMID29154948
PMCPMC5764226
OpenAlexW2769821670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.