Evidence map›Paper›PMID 29154897›Full record

ArticleMagnetic resonance imaging2018

Identification of ghost artifact using texture analysis in pediatric spinal cord diffusion tensor images.

Mahdi Alizadeh, Chris J Conklin, Devon M Middleton, Pallav Shah, Sona Saksena, Laura Krisa, Jürgen Finsterbusch, Scott H Faro, M J Mulcahey, Feroze B Mohamed

Abstract read
In one paragraph

Article in Magnetic resonance imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. [Artificial intelligence in image evaluation and diagnosis].Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mahdi AlizadehJefferson Integrated Magnetic Resonance Imaging Center, Department of Radiology, Thomas Jefferson University, Philadelphia, PA, United States; Department of Neurosurgery, Thomas Jefferson University, Philadelphia, PA, United States. Electronic address: mahdi.alizadeh.2@jefferson.edu.
Chris J ConklinJefferson Integrated Magnetic Resonance Imaging Center, Department of Radiology, Thomas Jefferson University, Philadelphia, PA, United States.
Devon M MiddletonJefferson Integrated Magnetic Resonance Imaging Center, Department of Radiology, Thomas Jefferson University, Philadelphia, PA, United States.
Pallav ShahDepartment of Radiology, Temple University, Philadelphia, PA, United States.
Sona SaksenaJefferson Integrated Magnetic Resonance Imaging Center, Department of Radiology, Thomas Jefferson University, Philadelphia, PA, United States.
Laura KrisaDepartment of Occupational Therapy, Thomas Jefferson University, Philadelphia, PA, United States.
Jürgen FinsterbuschDepartment of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Scott H FaroDepartment of Radiology, Johns Hopkins University, Baltimore, MD, United States.
M J MulcaheyDepartment of Occupational Therapy, Thomas Jefferson University, Philadelphia, PA, United States.
Feroze B MohamedJefferson Integrated Magnetic Resonance Imaging Center, Department of Radiology, Thomas Jefferson University, Philadelphia, PA, United States.

Funding

Neuroimaging based on DTI as a biomarker for spinal cord injury in children.R01NS079635 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI MOHAMED, FEROZE B, MULCAHEY-HERSHEY, MARYJANE · 2013 to 2017
$1.7M
NINDS NIH HHS R01 NS079635
6 · The paper itself

Abstract

purposeGhost artifacts are a major contributor to degradation of spinal cord diffusion tensor images. A multi-stage post-processing pipeline was designed, implemented and validated to automatically remove ghost artifacts arising from reduced field of view diffusion tensor imaging (DTI) of the pediatric spinal cord.

methodA total of 12 pediatric subjects including 7 healthy subjects (mean age=11.34years) with no evidence of spinal cord injury or pathology and 5 patients (mean age=10.96years) with cervical spinal cord injury were studied. Ghost/true cords, labeled as region of interests (ROIs), in non-diffusion weighted b0 images were segmented automatically using mathematical morphological processing. Initially, 21 texture features were extracted from each segmented ROI including 5 first-order features based on the histogram of the image (mean, variance, skewness, kurtosis and entropy) and 16s-order feature vector elements, incorporating four statistical measures (contrast, correlation, homogeneity and energy) calculated from co-occurrence matrices in directions of 0°, 45°, 90° and 135°. Next, ten features with a high value of mutual information (MI) relative to the pre-defined target class and within the features were selected as final features which were input to a trained classifier (adaptive neuro-fuzzy interface system) to separate the true cord from the ghost cord.

resultsThe implemented pipeline was successfully able to separate the ghost artifacts from true cord structures. The results obtained from the classifier showed a sensitivity of 91%, specificity of 79%, and accuracy of 84% in separating the true cord from ghost artifacts.

conclusionThe results show that the proposed method is promising for the automatic detection of ghost cords present in DTI images of the spinal cord. This step is crucial towards development of accurate, automatic DTI spinal cord post processing pipelines.

Indexed as

ArtifactsDiffusion Tensor ImagingChildFalse Positive ReactionsFemaleFuzzy LogicHealthy VolunteersHumansMaleNormal DistributionReproducibility of ResultsSensitivity and SpecificitySpinal CordSpinal Cord InjuriesClassificationDiffusion tensorGhost artifactPediatric spinal cordSegmentation

Identifiers

PMID29154897
PMCPMC5905435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.