Evidence map›Paper›PMID 29153680›Full record

ArticlePregnancy hypertension2017

Associations between bacterial infections and blood pressure in pregnancy.

Clive J Petry, Ken K Ong, Ieuan A Hughes, Carlo L Acerini, David B Dunger

Open access · hybridAbstract read
In one paragraph

Article in Pregnancy hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Current Evidence of Maternal Infection With Chlamydia trachomatis and Preeclampsia Risk.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025
    Review
  2. Article
  3. Risk factors for neonatal group B streptococcus vertical transmission: a prospective cohort study of 1815 mother-baby pairs.Journal of perinatology : official journal of the California Perinatal Association · 2018
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Clive J PetryDepartment of Paediatrics, University of Cambridge, Cambridge, UK. Electronic address: cjp1002@cam.ac.uk.
Ken K OngDepartment of Paediatrics, University of Cambridge, Cambridge, UK; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, UK.
Ieuan A HughesDepartment of Paediatrics, University of Cambridge, Cambridge, UK.
Carlo L AceriniDepartment of Paediatrics, University of Cambridge, Cambridge, UK.
David B DungerDepartment of Paediatrics, University of Cambridge, Cambridge, UK; The Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
University of Cambridge · GBMedical Research Council · GB

Funding

Diabetes UK 11/0004241Medical Research Council G0500733Medical Research Council G0600717Medical Research Council MC_UU_12015/2Wellcome Trust
6 · The paper itself

Abstract

objectivesTo test the hypothesis that bacterial infections in pregnancy are related to maternal blood pressure. STUDY

designBacterial infection was assessed using antibiotic usage as a surrogate and its association with blood pressure in pregnancy tested in the Cambridge Baby Growth Study.

main outcome measuresAntibiotic usage in pregnancy was self-reported in questionnaires. Blood pressure measurements at four time points in pregnancy were collected from the hospital notes of 622 women.

resultsUsing all the available blood pressure readings (adjusted for weeks gestation) antibiotic usage was associated with a higher mean arterial blood pressure across pregnancy: antibiotics used 85(84, 87)mmHg vs. no antibiotics used 83 (83, 84) mmHg (β=2.3 (0.6, 4.0) mmHg, p=9.6×10

conclusionsBacterial infection in pregnancy, as assessed by self-reported antibiotic usage, is associated with small rises in blood pressure.

Indexed as

AdultAnti-Bacterial AgentsBlood Pressure DeterminationFemaleGestational AgeHumansInfant, NewbornLongitudinal StudiesPre-EclampsiaPregnancyPregnancy Complications, InfectiousPregnancy TrimestersProspective StudiesUnited KingdomUrinary Tract InfectionsAnti-Bacterial AgentsAntibioticsGestational hypertensionPre-eclampsiaPregnancy

Identifiers

PMID29153680
PMCPMC5710763
OpenAlexW2755171716

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.