Evidence map›Paper›PMID 29153624›Full record

ArticleUrologic oncology2018

The effect of socioeconomic status, race, and insurance type on newly diagnosed metastatic prostate cancer in the United States (2004-2013).

Adam B Weiner, Richard S Matulewicz, Jeffrey J Tosoian, Joseph M Feinglass, Edward M Schaeffer

Abstract read
In one paragraph

Article in Urologic oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. Are we there yet? Closing the gap of prostate cancer presentation disparities in Ireland.Archives of public health = Archives belges de sante publique · 2024
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  20. The association of low socioeconomic status with advanced stage thyroid cancer.Journal of Taibah University Medical Sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adam B WeinerDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Richard S MatulewiczDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Jeffrey J TosoianJames Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Baltimore, MD.
Joseph M FeinglassDepartment of General Internal Medicine and Geriatrics, Northwestern University Feinberg School of Medicine, Chicago, IL.
Edward M SchaefferDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL. Electronic address: e-schaeffer@northwestern.edu.

Funding

Targeting FOXA1-downstream pathways: a novel therapeutic strategy for castration-resistant prostate cancerP50CA180995 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ABDULKADIR, SARKI A., HUSSAIN, MAHA H · 2015 to 2025
$19.9M
Multidiciplinary Integrative Genomic Approach to Distinguish Lethal from Indolent Prostate Cancer in Men of Europena and African AncestryU01CA196390 · NCI · JOHNS HOPKINS UNIVERSITY · PI DE MARZO, ANGELO MICHAEL, PIENTA, KENNETH J. · 2015 to 2020
$5.8M
NCI NIH HHS P50 CA180995NCI NIH HHS U01 CA196390
6 · The paper itself

Abstract

backgroundUnderstanding the characteristics of men who initially present with metastatic prostate cancer (mPCa) can better enable directed improvement initiatives. The objective of this study was to assess the relationship between socioeconomic status (SES) and newly diagnosed mPCa. MATERIALS

methodsAll men diagnosed with PCa in the National Cancer Data Base from 2004 to 2013 were identified. Characteristics of men presenting with and without metastatic disease were compared. A 4-level composite metric of SES was created using Census-based income and education data. Multivariable logistic regression was used to evaluate the association between SES, race/ethnicity, and insurance and the risk of presenting with mPCa at the time of diagnosis.

resultsOf 1,034,754 patients diagnosed with PCa, 4% had mPCa at initial presentation. Lower SES (first vs. fourth quartile; odds ratio [OR] = 1.39, 95% CI: 1.35-1.44), black and Hispanic race/ethnicity (vs. white; OR = 1.47, 95% CI: 1.43-1.51 and OR = 1.22, 95% CI: 1.17-1.28, respectively), and having Medicaid or no insurance (vs. Medicare or private; OR = 3.91, 95% CI: 3.78-4.05) were each independently associated with higher odds of presenting with mPCa after adjusting for all other covariates.

conclusionsLower SES, race/ethnicity, and having Medicaid or no insurance were each independently associated with higher odds of presenting with metastases at the time of PCa diagnosis. Our findings may partially explain current PCa outcomes disparities and inform future efforts to reduce disparities.

Indexed as

Social ClassAdenocarcinomaAgedHumansInsurance, HealthMaleMedicaidMiddle AgedProstatic NeoplasmsRacial GroupsRegistriesUnited StatesEpidemiologyNeoplasm metastasisProstatic neoplasmsUnited States

Identifiers

PMID29153624
PMCPMC6048442

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.