Evidence map›Paper›PMID 29153619›Full record

ArticleInternational journal of medical microbiology : IJMM2018

The use of stool specimens reveals Helicobacter pylori strain diversity in a cohort of adolescents and their family members in a developed country.

Brendan Dolan, Lucy Burkitt-Gray, Stephen Shovelin, Billy Bourke, Brendan Drumm, Marion Rowland, Marguerite Clyne

Open access · hybridAbstract read
In one paragraph

Article in International journal of medical microbiology : IJMM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Detection ofGhana medical journal · 2024
    Article
  4. Direct Detection of Antibiotic Resistance in ChineseJournal of healthcare engineering · 2022
    Article
  5. Contribution ofFrontiers in immunology · 2022
    Article
  6. Antibiotic resistance ofFrontiers in cellular and infection microbiology · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Brendan DolanSchool of Medicine, University College Dublin, Dublin, Ireland; Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland. Electronic address: brendan.dolan@medkem.gu.se.
Lucy Burkitt-GraySchool of Medicine, University College Dublin, Dublin, Ireland; Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland. Electronic address: lucy.burkitt-gray@ucdconnect.ie.
Stephen ShovelinSchool of Medicine, University College Dublin, Dublin, Ireland. Electronic address: shovlinstephen@gmail.com.
Billy BourkeSchool of Medicine, University College Dublin, Dublin, Ireland; Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland; The National Childrens Research Centre, Crumlin, Dublin, Ireland. Electronic address: billy.bourke@ucd.ie.
Brendan DrummSchool of Medicine, University College Dublin, Dublin, Ireland. Electronic address: brendan.drumm@ucd.ie.
Marion RowlandSchool of Medicine, University College Dublin, Dublin, Ireland. Electronic address: marion.rowland@ucd.ie.
Marguerite ClyneSchool of Medicine, University College Dublin, Dublin, Ireland; Conway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland. Electronic address: marguerite.clyne@ucd.ie.
University College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori infection occurs within families but the transmission route is unknown. The use of stool specimens to genotype strains facilitates inclusion of complete families in transmission studies. Therefore, we aimed to use DNA from stools to analyze strain diversity in H. pylori infected families. We genotyped H. pylori strains using specific biprobe qPCR analysis of glmM, recA and hspA. Concentration of H. pylori organisms before DNA isolation enhanced subsequent DNA amplification. We isolated H. pylori DNA from 50 individuals in 13 families. T

Indexed as

AdolescentAdultBacterial ProteinsDeveloped CountriesDNA, BacterialFamilyFecesGastric MucosaGenotypeHeat-Shock ProteinsHelicobacter InfectionsHelicobacter pyloriHumansMiddle AgedPhosphoglucomutaseRec A RecombinasesBacterial ProteinsDNA, BacterialHeat-Shock ProteinsHspA protein, bacteriaPhosphoglucomutaseRec A RecombinasesBiprobe assayFecal specimensGenotypingHelicobacter pyloriqPCR

Identifiers

PMID29153619
PMCPMC5864523
OpenAlexW2770541458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.