Evidence map›Paper›PMID 29153491›Full record

ArticleAnnals of epidemiology2018

Measures of human immunodeficiency virus (HIV) community viral load and HIV incidence among people who inject drugs.

Cristie Glasheen, Eric O Johnson, Jennifer Lorvick, Alex H Kral

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cristie GlasheenRTI International, Research Triangle Park, NC. Electronic address: cglasheen@rti.org.
Eric O JohnsonRTI International, Research Triangle Park, NC.
Jennifer LorvickRTI International, Research Triangle Park, NC.
Alex H KralRTI International, Research Triangle Park, NC.

Funding

Enhancing Discovery of HIV Host Genetics using Drug Abuse and other InteractionsR01DA038632 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI JOHNSON, ERIC OTTO · 2014 to 2018
$3.7M
Genome-Wide Association Study of HIV-1 Host Genetics Among Injection Drug UsersR01DA026141 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI JOHNSON, ERIC OTTO · 2008 to 2012
$3.5M
Assessing Patterns of HIV Risk Among IDUs in Neighborhood Environments over TimeR01DA023377 · NIDA · RESEARCH TRIANGLE INSTITUTE · PI KRAL, ALEXANDER H · 2009 to 2011
$1.4M
Geospatial Research on HIV Treatment in San FranciscoR15AI106466 · NIAID · SAN FRANCISCO STATE UNIVERSITY · PI MARTINEZ, ALEXIS · 2014 to 2014
$492k
NIAID NIH HHS R15 AI106466NIDA NIH HHS R01 DA023377NIDA NIH HHS R01 DA026141NIDA NIH HHS R01 DA038632
6 · The paper itself

Abstract

purposeTo evaluate the measures of community human immunodeficiency virus (HIV) viral load (VL) and the association with HIV incidence among people who inject drugs (PWID).

methodsData were from 1986 to 1999 Urban Health Study conducted among PWID in the San Francisco Bay Area. Extant measures of community VL use mean VL among HIV + study participants, not accounting for the proportion of HIV- individuals. We compared the strength of the associations between HIV incidence and the traditionally measured mean community VL and a new prevalence-adjusted community VL, calculated by dividing the sum of VL among HIV + participants by the total participants irrespective of HIV status.

resultsMean community VL was not correlated with HIV incidence in this sample of PWID (r

conclusionsThe effect of community VL on HIV incidence may be stronger than previously reported. Future studies of community VL surveillance should consider accounting for the prevalence of HIV using a prevalence-adjusted community VL measure.

Indexed as

Viral LoadAdultAnti-HIV AgentsCross-Sectional StudiesFemaleHIV InfectionsHumansIncidenceMaleMiddle AgedSan FranciscoSubstance Abuse, IntravenousViremiaAnti-HIV AgentsCommunity viral loadHIVHIV epidemiologyHIV incidencePeople who inject drugsViral load

Identifiers

PMID29153491
PMCPMC5807197

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.