ArticleEuropean journal of radiology2017
Application of arterial spin labeling perfusion MRI to differentiate benign from malignant intracranial meningiomas.
Article in European journal of radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 53 citations in OpenAlex.
- Delta Histogram Analysis of Synthetic MRI for Evaluating Grade and Cellular Proliferation of Meningioma.Radiology. Imaging cancer · 2026Article
- Does arterial spin labelling represent a valid alternative to other MR perfusion techniques in neuro-oncology?La Radiologia medica · 2025Review
- Malignant Meningiomas: From Diagnostics to Treatment.Diagnostics (Basel, Switzerland) · 2025Review
- The relationship between molecular subtypes and magnetic resonance perfusion in patients with brain meningioma.Surgical neurology international · 2025Article
- Arterial spin labeled perfusion MRI for the assessment of radiation-treated meningiomas.Frontiers in radiology · 2024Article
- Insights Into Meningioma Visibility on Arterial Spin Labeling MRI: Location Outweighs Size.Cureus · 2023Article
- Arterial spin labeling clinical applications for brain tumors and tumor treatment complications: A comprehensive case-based review.The neuroradiology journal · 2023Review
- Effects of Post-Labeling Delay on Magnetic Resonance Evaluation of Brain Tumor Blood Flow Using Arterial Spin Labeling.Tomography (Ann Arbor, Mich.) · 2023Article
- Imaging Characteristics of Meningiomas.Advances in experimental medicine and biology · 2023Article
- Use of advanced neuroimaging and artificial intelligence in meningiomas.Brain pathology (Zurich, Switzerland) · 2022Review
- Differentiation between various types and subtypes of intracranial meningiomas with advanced MRI.SA journal of radiology · 2022Article
- Giant Intraparenchymal Meningioma in a Female Child: Case Report and Literature Review.Cancer management and research · 2021Article
- Multi-parametric qualitative and quantitative MRI assessment as predictor of histological grading in previously treated meningiomas.Neuroradiology · 2020Article
- Grading meningiomas utilizing multiparametric MRI with inclusion of susceptibility weighted imaging and quantitative susceptibility mapping.Journal of neuroradiology = Journal de neuroradiologie · 2020Article
- Pseudo-continuous arterial spin labelling shows high diagnostic performance in the detection of postoperative residual lesion in hyper-vascularised adult brain tumours.European radiology · 2020Article
- Arterial Spin Labeling for Glioma Grade Discrimination: Correlations with IDH1 Genotype and 1p/19q Status.Translational oncology · 2019Article
- Imaging and diagnostic advances for intracranial meningiomas.Neuro-oncology · 2019Review
- Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
purposeDifferentiating WHO grade I-III of meningioma by non-invasive imaging is challenging. This study investigated the potential of MR arterial spin labeling (ASL) to establish tumor grade in meningioma patients. MATERIAL AND
methodsPseudo-continuous ASL with 3D background suppressed gradient and spin echo (GRASE) was acquired on 54 patients with newly diagnosed or recurrent intracranial meningioma. Perfusion patterns characterized in CBF color maps were independently evaluated by three neuroradiologists blinded to patient history, and correlated with tumor grade from histo-pathological review.
resultsThree perfusion patterns could be discerned by visual evaluation of CBF maps. Pattern 1 consisted of homogeneous hyper-perfusion of the entire tumor; pattern 2 demonstrated heterogeneous hyper-perfusion; pattern 3 showed no substantial hyper-perfusion. Evaluation of the perfusion patterns was highly concordant among the three readers (Kendall W=0.9458, P<0.0001). Pattern 1 was associated with WHO Grade I meningioma of (P<0.0001). Patterns 2 and 3 were predictive of WHO Grade II and III meningioma (P<0.0001), with an odds ratio (OR, versus pattern 1) of 49.6 (P<0.01) in a univariate analysis, and an OR of 186.4 (P<0.01) in a multivariate analysis.
conclusionQualitative evaluation of ASL CBF maps can help differentiate benign (WHO Grade I) from higher grade (WHO Grade II and III) intracranial meningiomas, potentially impacting therapeutic strategy.
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