ArticleBirth defects research2017
Population-based birth defects data in the United States, 2010-2014: A focus on gastrointestinal defects.
Article in Birth defects research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.
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Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Global prognostic factors for mortality and major postoperative morbidity in neonatal intestinal atresia in the modern surgical era: a systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
- Preservation of the azygos vein versus ligation of the azygos vein during primary surgical repair of congenital esophageal atresia.The Cochrane database of systematic reviews · 2025Pooled it
- Necessity of Prophylactic Extrapleural Chest Tube During Primary Surgical Repair of Esophageal Atresia: A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2022Pooled it
- A new tool for pregnancy research: a unified definition for major congenital malformation across ICD eras.American journal of epidemiology · 2026Article
- The Use of Botulinum Toxin Type A in Esophageal Atresia Management: a Randomized, Controlled, Investigator-blinded Feasibility and Exploratory Trial in Piglets.Scientific reports · 2026Article
- Genital and urinary tract malformations, associated morbidity, and need for urogenital surgery among children with esophageal atresia: a retrospective cohort study.Pediatric surgery international · 2026Article
- Analysis of Prevalence and Mortality Among Neonates and Children With Intestinal Atresia: A Multinational Study, 1974-2015.Birth defects research · 2026Article
- Peroral endoscopic tunneling stricturotomy for diverticulum treatment: novel procedure for pediatric esophageal anastomotic diverticula.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- Genetic evaluation and pregnancy outcome of fetuses with digestive system malformations: an eight-year single-center retrospective study.Frontiers in pediatrics · 2026Article
- A Rare Case of Apple Peel Ileal Atresia With Coexisting Colonic Atresia: Surgical Management and Outcomes.Cureus · 2025Article
- COVID-19 Vaccination During Pregnancy and Birth Defects: Results From the CDC COVID-19 Vaccine Pregnancy Registry, United States 2021-2022.Birth defects research · 2025Article
- Gastrointestinal Fistulas-What Gastroenterologists Need to Know in 2025.Canadian journal of gastroenterology & hepatology · 2025Review
- Article
- Enhanced estimation strategy for determining the location of tracheoesophageal fistula in a preterm, low-birth-weight infant with congenital esophageal atresia type C and duodenal atresia: a case report.JA clinical reports · 2024Article
- Prevalence and death rate of birth defects from population-based surveillance in Hunan Province, China, 2010-2020.Scientific reports · 2024Article
- Thoracoscopic primary repair is useful for esophageal atresia with tracheoesophageal fistula in neonates with low body weight.Pediatric surgery international · 2024Article
- Specific Birth Defects Following Antiseizure Medications Used By Pregnant Women With Epilepsy.Neurology. Clinical practice · 2024Article
- Multivariate logistic regression analysis of risk factors for birth defects: a study from population-based surveillance data.BMC public health · 2024Article
- Primary cilia are critical for tracheoesophageal septation.Developmental dynamics : an official publication of the American Association of Anatomists · 2024Article
- Scientific impact of the National Birth Defects Prevention Network multistate collaborative publications.Birth defects research · 2024Review
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
backgroundGastrointestinal defects are a phenotypically and etiologically diverse group of malformations. Despite their combined prevalence and clinical impact, little is known about the epidemiology of these birth defects. Therefore, the objective of the 2017 National Birth Defects Prevention Network (NBDPN) data brief was to better describe the occurrence of gastrointestinal defects.
methodsAs part of the 2017 NBDPN annual report, 28 state programs provided additional data on gastrointestinal defects for the period 2010-2014. Counts and prevalence estimates (per 10,000 live births) were calculated overall and by demographic characteristics for (1) biliary atresia; (2) esophageal atresia/tracheoesophageal fistula; (3) rectal and large intestinal atresia/stenosis; and (4) small intestinal atresia/stenosis. Additionally, we explored the frequency of these malformations co-occurring with other structural birth defects.
resultsPooling data from all participating registries, the prevalence estimates were: 0.7 per 10,000 live births for biliary atresia (713 cases); 2.3 per 10,000 live births for esophageal atresia/tracheoesophageal fistula (2,472 cases); 4.2 per 10,000 live births for rectal and large intestinal atresia/stenosis (4,334 cases); and 3.4 per 10,000 live births for small intestinal atresia/stenosis (3,388 cases). Findings related to co-occurring birth defects were especially notable for esophageal atresia/tracheoesophageal fistula, rectal and large intestinal atresia/stenosis, and small intestinal atresia/stenosis, where the median percentage of non-isolated cases was 53.9%, 45.5%, and 50.6%, respectively.
conclusionsThese population-based prevalence estimates confirm some previous studies, and provide a foundation for future epidemiologic studies of gastrointestinal defects. Exploring the genetic and environmental determinants of these malformations may yield new clues into their etiologies.
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