ArticleThe 2010 ACM International Conference on Bioinformatics and Computational Biology : ACM-BCB 2010 : Niagara Falls, New York, U.S.A., August 2-4, 2010. ACM International Conference on Bioinformatics and Computational Biology (1st : 2010 :...2010
Genome-wide compatible SNP intervals and their properties.
Article in The 2010 ACM International Conference on Bioinformatics and Computational Biology : ACM-BCB 2010 : Niagara Falls, New York, U.S.A., August 2-4, 2010. ACM International Conference on Bioinformatics and Computational Biology (1st : 2010 :..., 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Domestication Shapes Recombination Patterns in Tomato.Molecular biology and evolution · 2022Article
- An improved burden-test pipeline for identifying associations from rare germline and somatic variants.BMC genomics · 2017Article
- A performance study of the impact of recombination on species tree analysis.BMC genomics · 2016Article
- Mapping the genomic architecture of adaptive traits with interspecific introgressive origin: a coalescent-based approach.BMC genomics · 2016Article
- Informatics resources for the Collaborative Cross and related mouse populations.Mammalian genome : official journal of the International Mammalian Genome Society · 2015Review
- High-resolution sex-specific linkage maps of the mouse reveal polarized distribution of crossovers in male germline.Genetics · 2014Article
- Deconstructing Mus gemischus: advances in understanding ancestry, structure, and variation in the genome of the laboratory mouse.Mammalian genome : official journal of the International Mammalian Genome Society · 2013Review
- Comparative analysis and visualization of multiple collinear genomes.BMC bioinformatics · 2012Article
- The genome architecture of the Collaborative Cross mouse genetic reference population.Genetics · 2012Article
- Article
- Dynamic Visualization and Comparative Analysis of Multiple Collinear Genomic Data.ACM-BCB ... ... : the ... ACM Conference on Bioinformatics, Computational Biology and Biomedicine. ACM Conference on Bioinformatics, Computational Biology and Biomedicine · 2011Article
- Subspecific origin and haplotype diversity in the laboratory mouse.Nature genetics · 2011Article
- Inferring genome-wide mosaic structure.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Intraspecific genomes can be subdivided into blocks with limited diversity. Understanding the distribution and structure of these blocks will help to unravel many biological problems including the identification of genes associated with complex diseases, finding the ancestral origins of a given population, and localizing regions of historical recombination, gene conversion, and homoplasy. We present methods for partitioning a genome into blocks for which there are no apparent recombinations, thus providing parsimonious sets of compatible genome intervals based on the four-gamete test. Our contribution is a thorough analysis of the problem of dividing a genome into compatible intervals, in terms of its computational complexity, and by providing an achievable lower-bound on the minimal number of intervals required to cover an entire data set. In general, such minimal interval partitions are not unique. However, we identify properties that are common to every possible solution. We also define the notion of an interval set that achieves the interval lower-bound, yet maximizes interval overlap. We demonstrate algorithms for partitioning both haplotype data from inbred mice as well as outbred heterozygous genotype data using extensions of the standard four-gamete test. These methods allow our algorithms to be applied to a wide range of genomic data sets.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.