Evidence map›Paper›PMID 29152610›Full record

ArticleTH open : companion journal to thrombosis and haemostasis2017

Mutations in Coagulation

Zheng Ping, Abha Soni, Lance A Williams, Huy P Pham, Malay K Basu, X Long Zheng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in TH open : companion journal to thrombosis and haemostasis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Factor VIII as a potential player in cancer pathophysiology.Journal of thrombosis and haemostasis : JTH · 2022
    Article
  2. Happy New Year!TH open : companion journal to thrombosis and haemostasis · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zheng PingDivisions of Laboratory Medicine, The University of Alabama at Birmingham, AL 35249.
Abha SoniDivisions of Laboratory Medicine, The University of Alabama at Birmingham, AL 35249.
Lance A WilliamsDivisions of Laboratory Medicine, The University of Alabama at Birmingham, AL 35249.
Huy P PhamDivisions of Laboratory Medicine, The University of Alabama at Birmingham, AL 35249.
Malay K BasuDivision of Informatics, Department of Pathology, The University of Alabama at Birmingham, AL 35249.
X Long ZhengDivisions of Laboratory Medicine, The University of Alabama at Birmingham, AL 35249.
University of Alabama at Birmingham · US

Funding

Pathogenesis of Thrombotic MicroangiopathyR01HL126724 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHENG, X. LONG · 2015 to 2018
$1.8M
Novel Therapeutics for Acquired Thrombotic Thrombocytopenic PurpuraR01HL115187 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHENG, X. LONG · 2013 to 2016
$1.6M
NHLBI NIH HHS R01 HL115187NHLBI NIH HHS R01 HL126724
6 · The paper itself

Abstract

Coagulation factor VIII (FVIII), von Willebrand factor (VWF), and ADAMTS13 play an important role in regulation of normal hemostasis. However, little is known about their roles in patients with malignancy, particularly with cutaneous melanoma. Whole genome sequencing data are available for 25,719 cases in 126 cancer genomic studies for analysis. All sequencing data and corresponding pathology findings were obtained from The Cancer Genome Atlas. The cBioportal bioinformatics tools were used for the data analysis. Our results demonstrated that mutations in genes encoding

Identifiers

PMID29152610
PMCPMC5690574
OpenAlexW2765963178

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.