Evidence map›Paper›PMID 29152589›Full record

ArticleAdvances in pediatric research2014

The Argentina Premature Asthma and Respiratory Team (APART): objectives, design, and recruitment results of a prospective cohort study of viruses and wheezing in very low birth weight infants.

Tatyana Plachco, Romina Libster, Jodell E Linder, Lucrecia Bossi, Norma Aspres, Gabriela Bauer, John V Williams, Fernando P Polack, E Kathryn Miller

Open access · greenAbstract read
In one paragraph

Article in Advances in pediatric research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Tatyana PlachcoHospital de Pediatria SAMIC Prof. Dr. Juan P Garrahan, Buenos Aires, Argentina.
Romina LibsterFundacion INFANT, Buenos Aires, Argentina.
Jodell E LinderDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Lucrecia BossiHospital de Pediatria SAMIC Prof. Dr. Juan P Garrahan, Buenos Aires, Argentina.
Norma AspresHospital Materno Infantil Ramón Sarda, Buenos Aires, Argentina.
Gabriela BauerHospital de Pediatria SAMIC Prof. Dr. Juan P Garrahan, Buenos Aires, Argentina.
John V WilliamsDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Fernando P PolackFundacion INFANT, Buenos Aires, Argentina.
E Kathryn MillerDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Vanderbilt University · USGarrahan Hospital · ARInfant Foundation · AR

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
VANTAGE:Consolidation to create the Vanderbilt Technologies for Advanced GenomicsG20RR030956 · NCRR · VANDERBILT UNIVERSITY · PI PIETENPOL, JENNIFER A · 2010 to 2010
$8.7M
The Role of Human Rhinoviruses in Premature Infant Respiratory Disease and AsthmaK23AI091691 · NIAID · VANDERBILT UNIVERSITY · PI MILLER, EVA KATHRYN · 2011 to 2015
$619k
NCATS NIH HHS UL1 TR000445NCI NIH HHS P30 CA068485NCRR NIH HHS G20 RR030956NCRR NIH HHS UL1 RR024975NEI NIH HHS P30 EY008126NIAID NIH HHS K23 AI091691
6 · The paper itself

Abstract

backgroundAsthma and wheezing account for a substantial disease burden around the world. Very low birth weight (VLBW, <1500 grams) infants are at an increased risk for the development of severe acute respiratory illness (ARI) and recurrent wheeze/asthma. The role of respiratory viruses in asthma predisposition in premature infants is not well understood. Preliminary evidence suggests that infection with human rhinovirus (RV) early in life may contribute to greater burden of asthma later in life.

methodsA prospective cohort study of premature VLBW infants from Buenos Aires, Argentina, was enrolled year-round during a three-year period in the neonatal intensive care unit and followed during every ARI and with monthly well visits during the first year of life. Longitudinal follow-up up until age five years is ongoing.

resultsThis report describes the objectives, design, and recruitment results of this prospective cohort. Two hundred and five patients were enrolled from August 2011 through January 2014, and follow-up is ongoing. A total of 319 ARI episodes were observed from August 2011 to July 2014, and 910 well visits occurred during this time period.

conclusionsThe Argentina Premature Asthma and Respiratory Team (APART) is a unique cohort consisting of over 200 patients and over 1200 specimens who have been and will continue to be followed intensively from NICU discharge to capture baseline risk factors and every ARI, with interceding well visits during the first year of life, as well as longitudinal follow-up to age 5 years for asthma and atopy outcomes.

Identifiers

PMID29152589
PMCPMC5687834
OpenAlexW2955811149

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.