ArticleBladder cancer (Amsterdam, Netherlands)2017
Chemotherapy Versus Chemoradiation for Node-Positive Bladder Cancer: Practice Patterns and Outcomes from the National Cancer Data Base.
Article in Bladder cancer (Amsterdam, Netherlands), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Bladder Preservation Therapy in Muscle-Invasive Bladder Cancer: Current Evidence and Future Directions.Journal of clinical medicine · 2026Review
- The role of radical cystectomy and lymphadenectomy in the management of bladder cancer with clinically positive lymph node involvement.Current opinion in urology · 2025Review
- Management of patients with muscle-invasive bladder cancer with clinical evidence of pelvic lymph node metastases.Nature reviews. Urology · 2024Review
- A comparative analysis of radical cystectomy with perioperative chemotherapy, chemoradiation therapy, or systemic therapy in patients with clinically advanced node-positive bladder cancer (cN2/N3).Frontiers in oncology · 2023Article
- Management of Clinically Regional Node-Positive Urothelial Carcinoma of the Bladder.Current oncology reports · 2021Review
- Long-term outcomes by response to neoadjuvant chemotherapy or chemoradiation in patients with resected pancreatic adenocarcinoma.Journal of gastrointestinal oncology · 2019Article
- National Cancer Database report of nonmetastatic esophageal small cell carcinoma.Cancer medicine · 2018Article
- Chemoradiotherapy versus chemotherapy alone for unresected intrahepatic cholangiocarcinoma: practice patterns and outcomes from the national cancer data base.Journal of gastrointestinal oncology · 2018Article
- Utilization of intensity modulated radiation therapy for anal cancer in the United States.Journal of gastrointestinal oncology · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundManagement of clinically node-positive bladder cancer (cN+ BC) is poorly defined; national guidelines recommend chemotherapy (CT) alone or chemoradiation (CRT).
objectiveUsing a large, contemporary dataset, we evaluated national practice patterns and outcomes of CT versus CRT to elucidate the optimal therapy for this patient population.
methodsThe National Cancer Data Base (NCDB) was queried (2004-2013) for patients diagnosed with cT
resultsOf 1,783 total patients, 1,388 (77.8%) underwent CT alone, and 395 (22.2%) CRT. Although patients receiving CRT tended to be of higher socioeconomic status, they were more likely older (
conclusionsCRT is underutilized in the United States for cN+ BC but is independently associated with improved survival despite being preferentially administered to a somewhat higher-risk population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.