ArticleJournal of translational neuroscience2016
Why sex differences in schizophrenia?
Article in Journal of translational neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
115 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association between autism and psychosis and the tools used to measure it: An updated systematic review and meta-analysis.The British journal of clinical psychology · 2026Pooled it
- Relationships between early age at onset of psychotic symptoms and treatment resistant schizophrenia.Early intervention in psychiatry · 2022Trial
- The role of plasma oxytocin in early-onset schizophrenia: implications for disease severity and early intervention.BMC psychiatry · 2026Article
- Envisioning Cannabinoid CB1 Receptor Biased Signaling as a Therapeutic Target for Schizophrenia.The American journal of psychiatry · 2026Review
- Large-scale automated detection reveals pervasive sex imbalance in biomedical research.bioRxiv : the preprint server for biology · 2026Article
- Schizophrenia-related suicide mortality in the United States by sex, 1999-2023.Discover mental health · 2026Article
- Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study.Acta psychiatrica Scandinavica · 2026Article
- The impact of a national exercise intervention on lifestyle habits among individuals with schizophrenia spectrum disorders: results from the FitForLife intervention study.BMC research notes · 2026Article
- Aging in Schizophrenia: Perspectives on Molecular Mechanisms and a Mini-review.Schizophrenia bulletin · 2026Review
- Diagnostic Conversion From Psychotic Unipolar Depression to Bipolar and Psychotic Disorders: A Swedish Registry-Based Study.Acta psychiatrica Scandinavica · 2026Article
- Burden, Incidence, and Spatial Distribution of Schizophrenia in Ecuador (2010-2021): A Nationwide Hospital Discharge Analysis.International journal of environmental research and public health · 2026Observational
- Associations between serum tumor necrosis factor-alpha, hippocampal-prefrontal-ventricular volumes, and clinical profiles in schizophrenia: a biomarker and neuroimaging study in North Sumatera, Indonesia.Frontiers in psychiatry · 2026Article
- A scoping review of genetic studies of treatment-resistant schizophrenia.Frontiers in genetics · 2026Review
- Sex-specific transcriptome similarity networks elucidate comorbidity relationships.Communications medicine · 2025Article
- Altered Network Function in Hippocampus After Sub-Chronic Activation of Cannabinoid Receptors in Early Adolescence.International journal of molecular sciences · 2025Article
- The language of paranoia: linguistic analysis of SMI speech with considerations of race and sex.Journal of mental health (Abingdon, England) · 2025Article
- Evenamide reverses schizophrenia-related dysfunction in a neurodevelopmental animal model.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Altered network function in hippocampus after sub-chronic activation of Cannabis receptors in peri-adolescence.bioRxiv : the preprint server for biology · 2025Article
- Risk Factors for Late-Onset Psychosis: A Case-Control Study.Schizophrenia bulletin · 2025Article
- 17β-estradiol status alters NMDAR function and antipsychotic-like activity in female rats.Molecular psychiatry · 2025Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Clinical observation shows that men and women are different in prevalence, symptoms, and responses to treatment of several psychiatric disorders, including schizophrenia. While the etiology of gender differences in schizophrenia is only partially understood, recent genetic studies suggest significant sex-specific pathways in the schizophrenia between men and women. More research is needed to understand the causal roles of sex differences in schizophrenia in order to ultimately develop sex-specific treatment of this serious mental illness. In the present review, we will outline the current evidence on the sex-related factors interaction with disease onset, symptoms and treatment of schizophrenia, and discuss the potential molecular mechanisms that may mediate their cooperative actions in schizophrenia pathogenesis.
Indexed as
Identifiers
29152382PMC5688947What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.