Evidence map›Paper›PMID 29152322›Full record

ReviewJournal of animal science and technology2017

Choosing a culture medium for SCNT and iSCNT reconstructed embryos: from domestic to wildlife species.

A Cordova, W A King, G F Mastromonaco

Open access · goldAbstract readReview
In one paragraph

Review in Journal of animal science and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

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  12. Insights into the roles of sperm in animal cloning.Stem cell research & therapy · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

A CordovaDepartment of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario Canada.
W A KingDepartment of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario Canada.
G F MastromonacoDepartment of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario Canada.
University of Guelph · CAToronto Zoo · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decades, in vitro culture media have been developed to successfully support IVF embryo growth in a variety of species. Advanced reproductive technologies, such as somatic cell nuclear transfer (SCNT), challenge us with a new type of embryo, with special nutritional requirements and altered physiology under in vitro conditions. Numerous studies have successfully reconstructed cloned embryos of domestic animals for biomedical research and livestock production. However, studies evaluating suitable culture conditions for SCNT embryos in wildlife species are scarce (for both intra- and interspecies SCNT). Most of the existing studies derive from previous IVF work done in conventional domestic species. Extrapolation to non-domestic species presents significant challenges since we lack information on reproductive processes and embryo development in most wildlife species. Given the challenges in adapting culture media and conditions from IVF to SCNT embryos, developmental competence of SCNT embryos remains low. This review summarizes research efforts to tailor culture media to SCNT embryos and explore the different outcomes in diverse species. It will also consider how these culture media protocols have been extrapolated to wildlife species, most particularly using SCNT as a cutting-edge technical resource to assist in the preservation of endangered species.

Indexed as

Culture mediaDomestic speciesEmbryosin vitro cultureNutrientsSomatic cell nuclear transferWildlife species

Identifiers

PMID29152322
PMCPMC5680814
OpenAlexW2765778582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.