Evidence map›Paper›PMID 29152320›Full record

ArticleFertility research and practice2017

Intramuscular progesterone (Gestone) versus vaginal progesterone suppository (Cyclogest) for luteal phase support in cycles of in vitro fertilization-embryo transfer: patient preference and drug efficacy.

Amal Yaseen Zaman, Serdar Coskun, Ahmed Abdullah Alsanie, Khalid Arab Awartani

Open access · hybridAbstract read
In one paragraph

Article in Fertility research and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Amal Yaseen ZamanKing Faisal Specialist Hospital and Research Center and Taibah University, Zahrawi St، Al Maather, Riyadh, 12713 Saudi Arabia.
Serdar CoskunKing Faisal Specialist Hospital and Research Center and Alfaisal University, Zahrawi St، Al Maather, Riyadh, 12713 Saudi Arabia.
Ahmed Abdullah AlsanieKing Faisal Specialist Hospital and Research Center, Zahrawi St، Al Maather, Riyadh, 12713 Saudi Arabia.
Khalid Arab AwartaniKing Faisal Specialist Hospital and Research Center and Alfaisal University, Zahrawi St، Al Maather, Riyadh, 12713 Saudi Arabia.
Alfaisal University · SATaibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe requirement for luteal phase support (LPS) in stimulated IVF cycles is well established, however drug choice, and route of administration and duration of use are not. This report evaluates patients' preference and satisfaction by using either vaginal or intramuscular (IM) progesterone (P) supplementation for luteal phase support after in vitro fertilization and embryo transfer (IVF-ET).

methodsIt is a prospective cohort study done in a reproductive and infertility unit in a tertiary care hospital from March 2013 through February 2015 for four hundred and nine patients undergoing IVF-ET. Patients were allowed to choose either vaginal or IM P for LPS. Patient preference and satisfaction, as well as differences in clinical pregnancy rates between the two groups were assessed at one or two time points throughout the study.

resultsThere were no statistically significant differences in the patients' characteristics and clinical outcomes between the two groups. There were 88 pregnancies (38.8%) among patients treated with vaginal p and 62 pregnancies (34%) among IM P patients. Average satisfaction score at the pregnancy test and ultrasound (U/S) visits was similar between both groups.

conclusionsPatients' satisfaction and pregnancy rates were similar between vaginal and IM P supplementation.

Indexed as

IntramuscularIn vitro fertilizationLuteal phase supportPregnancy rateProgesteroneVaginal

Identifiers

PMID29152320
PMCPMC5679140
OpenAlexW2767718584

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.