ArticleJournal of nutritional science2017
Effects of monobutyrin and tributyrin on liver lipid profile, caecal microbiota composition and SCFA in high-fat diet-fed rats.
Article in Journal of nutritional science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- The Effects of Dietary Pattern during Intensified Training on Stool Microbiota of Elite Race Walkers.Nutrients · 2019Trial
- Effects of Tributyrin Supplementation in High-Soybean-Meal Diet on Growth Performance, Hemolymph and Hepatopancreas Immune and Antioxidant Parameters, and Intestinal Morphology of Juvenile Pacific White Shrimp (Animals : an open access journal from MDPI · 2026Article
- Butyric glycerides enhance resistance of chicken enterocytes to pathogen adhesion and cytotoxicity in vitro.Veterinary research communications · 2026Article
- Stratified dietary inflammatory potential identifies oral and gut microbiota differences associated with cognitive function in older adults.Scientific reports · 2025Article
- Article
- Effects of Supplementing Tributyrin on Meat Quality Characteristics of Foreshank Muscle of Weaned Small-Tailed Han Sheep Lambs.Animals : an open access journal from MDPI · 2024Article
- The Role of Gut Microbiome-Derived Short-Chain Fatty Acid Butyrate in Hepatobiliary Diseases.The American journal of pathology · 2023Review
- Article
- Butyrate Glycerides Protect against Intestinal Inflammation and Barrier Dysfunction in Mice.Nutrients · 2022Article
- Monobutyrin and monovalerin improve gut-blood-brain biomarkers and alter gut microbiota composition in high-fat fed apolipoprotein-E-knockout rats.Scientific reports · 2022Article
- Butyrate: Connecting the gut-lung axis to the management of pulmonary disorders.Frontiers in nutrition · 2022Review
- FermentedFrontiers in pharmacology · 2022Article
- Effects of Dietary Tributyrin on Growth Performance, Biochemical Indices, and Intestinal Microbiota of Yellow-Feathered Broilers.Animals : an open access journal from MDPI · 2021Article
- Biological Function of Short-Chain Fatty Acids and Its Regulation on Intestinal Health of Poultry.Frontiers in veterinary science · 2021Review
- Article
- Dietary tributyrin supplementation and submaximal exercise promote activation of equine satellite cells.Journal of animal science · 2019Article
- Monobutyrin Reduces Liver Cholesterol and Improves Intestinal Barrier Function in Rats Fed High-Fat Diets.Nutrients · 2019Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Butyric acid has been shown to have suppressive effects on inflammation and diseases related to the intestinal tract. The aim of the present study was to investigate whether supplementation of two glycerol esters, monobutyrin (MB) and tributyrin (TB), would reach the hindgut of rats, thus having an effect on the caecal profile of SCFA, microbiota composition and some risk markers associated with chronic inflammation. For this purpose, rats were fed high-fat diets after adding MB (1 and 5 g/kg) and TB (5 g/kg) to a diet without any supplementation (high-fat control; HFC). A low-fat (LF) diet was also included. In the liver, total cholesterol concentrations, LDL-cholesterol concentrations, LDL:HDL ratio, and succinic acid concentrations were reduced in rats given the MB and TB (5 g/kg) diets, compared with the group fed the HFC diet. These effects were more pronounced in MB than TB groups as also expressed by down-regulation of the gene
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.