Evidence map›Paper›PMID 29152228›Full record

ReviewF1000Research2017

CD1: From Molecules to Diseases.

D Branch Moody, Sara Suliman

Abstract readReview
In one paragraph

Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. CD1a and skin T cells: a pathway for therapeutic intervention.Clinical and experimental dermatology · 2024
    Review
  6. Review
  7. Article
  8. IdentifyingPeerJ · 2023
    Article
  9. Role of MHC class I pathways inFrontiers in cellular and infection microbiology · 2023
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

D Branch MoodyDivision of Rheumatology, Immunology Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Sara SulimanDivision of Rheumatology, Immunology Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5154-576X

Funding

Metabolomics Core U19AI111224 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI BASARABA, RANDALL J, MURRAY, MEGAN B · 2015 to 2021
$20.4M
T cell response to CDI-restricted lipids in tuberculosisR01AI049313 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2001 to 2025
$10.6M
CD1 Presentation of Self Lipids to Human T CellsR01AR048632 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2002 to 2024
$9.4M
Mechanism of action of HIV-1 VifR01AI043913 · NIAID · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI VOLSKY, DAVID J · 2001 to 2004
$1.2M
CD1 autoreactive T cells in human inflammatory skin diseaseR37AR048632 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI DAVID Branch MOODY · 2025 to 2026
$1.1M
MECHANISM OF ACTION OF HIV-1 VIFR21AI043913 · NIAID · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI VOLSKY, DAVID J · 2000 to 2000
$349k
NIAID NIH HHS R01 AI043913NIAID NIH HHS R01 AI049313NIAID NIH HHS R21 AI043913NIAID NIH HHS U19 AI111224NIAMS NIH HHS R01 AR048632NIAMS NIH HHS R37 AR048632
6 · The paper itself

Abstract

The human cluster of differentiation (CD)1 system for antigen display is comprised of four types of antigen-presenting molecules, each with a distinct functional niche: CD1a, CD1b, CD1c, and CD1d. Whereas CD1 proteins were thought solely to influence T-cell responses through display of amphipathic lipids, recent studies emphasize the role of direct contacts between the T-cell receptor and CD1 itself. Moving from molecules to diseases, new research approaches emphasize human CD1-transgenic mouse models and the study of human polyclonal T cells

Indexed as

antigen displayCD1T cell receptorTCR

Identifiers

PMID29152228
PMCPMC5664979

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.