Evidence map›Paper›PMID 29152157›Full record

ArticleJournal of oral microbiology2017

A dysbiotic mycobiome dominated by

Manosha Perera, Nezar Noor Al-Hebshi, Irosha Perera, Deepak Ipe, Glen C Ulett, David J Speicher, Tsute Chen, Newell W Johnson

Open access · goldAbstract read
In one paragraph

Article in Journal of oral microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Signaling pathways and targeted interventions for precancers.Signal transduction and targeted therapy · 2026
    Review
  6. Review
  7. Frontiers in cellular and infection microbiology · 2026
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Mycobiome: an underexplored kingdom in cancer.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  14. Review
  15. Review
  16. The role of the microbiome in head and neck squamous cell cancers.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Review
  17. Multidrug-ResistantThe Malaysian journal of medical sciences : MJMS · 2025
    Review
  18. Review
  19. Review
  20. Crosstalk Between Oral Microbiome and Cancer: Emerging Trends and Insights.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 5 countries.

Manosha PereraSchool of Dentistry and Oral Health, Griffith University, Queensland, Australia.
Nezar Noor Al-HebshiMaurice H. Kornberg School of Dentistry, Temple University, Philadelphia, USA.
Irosha PereraPreventive Oral Health Unit, The National Dental Hospital (Teaching), Colombo, Sri Lanka.
Deepak IpeSchool of Medical Science, Griffith University, Queensland, Australia.
Glen C UlettSchool of Medical Science, Griffith University, Queensland, Australia.ORCID 0000-0002-9638-8091
David J SpeicherMenzies Health Institute Queensland;Griffith University, Nathan, Australia.ORCID 0000-0002-1745-3263
Tsute ChenDepartment of Microbiology, Forsyth Institute, Cambridge, USA.
Newell W JohnsonSchool of Dentistry and Oral Health, Griffith University, Queensland, Australia.
Griffith University · AUNational Hospital of Sri Lanka · LKTemple University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to characterize the mycobiome associated with oral squamous-cell carcinoma (OSCC). DNA was extracted from 52 tissue biopsies (cases: 25 OSCC; controls: 27 intra-oral fibro-epithelial polyps [FEP]) and sequenced for the fungal internal transcribed spacer 2 region using Illumina™ 2 x300bp chemistry. Merged reads were classified to species level using a BLASTN-algorithm with UNITE's named species sequences as reference. Downstream analyses were performed using QIIME™ and linear discriminant analysis effect size. A total of 364 species representing 160 genera and two phyla (Ascomycota and Basidiomycota) were identified, with

Indexed as

carcinomaDNA ribosomal spacerFungihigh-throughput nucleotide sequencingmicrobiomemouthmycobiomesquamous cell

Identifiers

PMID29152157
PMCPMC5678454
OpenAlexW2604886469

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.