Evidence map›Paper›PMID 29151920›Full record

ArticleJournal of innovative optical health sciences2017

Viscoelasticity of amyloid plaques in transgenic mouse brain studied by Brillouin microspectroscopy and correlative Raman analysis.

Sara Mattana, Silvia Caponi, Francesco Tamagnini, Daniele Fioretto, Francesca Palombo

Abstract read
In one paragraph

Article in Journal of innovative optical health sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sara MattanaDepartment of Physics and Geology, University of Perugia, Perugia I-06123, Italy.
Silvia CaponiIstituto Officina dei Materiali del CNR (CNR-IOM) - Unità di Perugia Department of Physics and Geology, University of Perugia, Perugia I-06123, Italy.
Francesco TamagniniHatherly Laboratories, Medical School University of Exeter, Exeter EX4 4PS, UK.
Daniele FiorettoDepartment of Physics and Geology, University of Perugia, Perugia I-06123, Italy.
Francesca PalomboSchool of Physics and Astronomy, University of Exeter, Exeter EX4 4QL, UK.

Funding

Wellcome Trust 105618
6 · The paper itself

Abstract

Amyloidopathy is one of the most prominent hallmarks of Alzheimer's disease (AD), the leading cause of dementia worldwide, and is characterized by the accumulation of amyloid plaques in the brain parenchyma. The plaques consist of abnormal deposits mainly composed of an aggregation-prone protein fragment,

Indexed as

Alzheimer’simaginglight scatteringprotein misfoldingvibrational spectroscopy

Identifiers

PMID29151920
PMCPMC5687568

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.