ArticleLaser physics2016
The application of antimicrobial photodynamic therapy (aPDT) in dentistry: a critical review.
2 registry-linked trialsOpen access · greenAbstract read
In one paragraph
Article in Laser physics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 59 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
7.4field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Antimicrobial Photodynamic Therapy for the Elimination of Dental Black Stain: A Randomised Clinical Trial
Efficacy of Some Different Photosensitizers in Photodynamic Inactivation of Periodontal Pathogens:A Randomized Clinical Trial
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 188 citations in OpenAlex.
- Gingival crevicular fluid level of tumor necrosis factor-alpha as a valuable biomarker for estimation of the efficacy of adjunctive antimicrobial photodynamic therapy in stage II-IV periodontitis: a systematic review and meta-analysis.Lasers in medical science · 2024Pooled it
- Does aPDT reduce bacterial load in endodontic infected teeth? A systematic review and meta-analysis.Lasers in medical science · 2023Pooled it
- Effect of combined antimicrobial photodynamic therapy and photobiomodulation therapy in the management of recurrent herpes labialis: a randomized controlled trial.Scientific reports · 2025Trial
- Treatment of dental plaque biofilms using photodynamic therapy: a randomised controlled study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2021Trial
- Antimicrobial Photodynamic Therapy Associated With Systemic Treatment in Osteoradionecrosis: An In Vivo Study.Lasers in surgery and medicine · 2026Article
- Adjunctive Antimicrobial Photodynamic Therapy in Non-Surgical Periodontal Treatment: Clinical and Microbiological Insights from a Randomized Split-Mouth Trial.Healthcare (Basel, Switzerland) · 2026Article
- Quercetin: A Light in the Fight Against MRSA.MicrobiologyOpen · 2026Article
- Development of a Methylene Blue Carrier System in Gellan Gum for Application in Antimicrobial Photodynamic Therapy againstACS omega · 2025Article
- Unveiling the Mechanisms of Bacterial Resistance and Countermeasures.Pathogens (Basel, Switzerland) · 2025Review
- Antimicrobial photodynamic activity of a BODIPY on an alternative preclinical model Galleria mellonella.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025Article
- Evaluation of antimicrobial photodynamic therapy with erythrosine and blue light emitting diode for inactivation of Aggregatibacter actinomycetemcomitans.Lasers in medical science · 2025Article
- The effect of aPDT with natural and chemical photosensitizers on reduction of bacteria around orthodontic brackets.Lasers in medical science · 2025Article
- Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries.Microorganisms · 2025Article
- Unseen Enemy: Mechanisms of Multidrug Antimicrobial Resistance in Gram-Negative ESKAPE Pathogens.Antibiotics (Basel, Switzerland) · 2025Review
- Advances in smart stimuli-responsive materials for oral wound healing.Frontiers in chemistry · 2025Review
- Dentition Type as a Determinant of Microbial Load Reduction by Antimicrobial Photodynamic Therapy in Deep Dentin Caries: A Systematic Review and Meta-analysis.Journal of dentistry (Shiraz, Iran) · 2024Review
- The impact of antimicrobial photodynamic therapy on pain and oral health-related quality of life: A literature review.Journal of dental sciences · 2024Review
- Article
- Nanomaterials: innovative approaches for addressing key objectives in periodontitis treatment.RSC advances · 2024Review
- Role of Photodynamic Therapy in Osteonecrosis and Osteoradionecrosis of the Jaws: A Systematic Review.Journal of maxillofacial and oral surgery · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
E T CarreraDepartment of Restorative Dentistry, Araraquara School of Dentistry, Universidade Estadual Paulista-UNESP, Araraquara, SP 14801-903, Brazil.
H B DiasDepartment of Restorative Dentistry, Araraquara School of Dentistry, Universidade Estadual Paulista-UNESP, Araraquara, SP 14801-903, Brazil.
S C T CorbiDepartment of Diagnosis and Surgery, Araraquara School of Dentistry, Universidade Estadual Paulista-UNESP, Araraquara, SP 14801-903, Brazil.
R A C MarcantonioDepartment of Diagnosis and Surgery, Araraquara School of Dentistry, Universidade Estadual Paulista-UNESP, Araraquara, SP 14801-903, Brazil.
A C A BernardiDepartment of Biology and Health Sciences, University Center of Araraquara-UNIARA, Araraquara, SP 14801-340, Brazil.
V S BagnatoDepartment of Physics and Materials Science, University of Sao Paulo-USP, Physics Institute of Sao Carlos-IFSC, Sao Carlos, SP 13566-590, Brazil.
M R HamblinWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.
A N S RastelliDepartment of Restorative Dentistry, Araraquara School of Dentistry, Universidade Estadual Paulista-UNESP, Araraquara, SP 14801-903, Brazil.
Universidade Estadual Paulista (Unesp) · BRCentro Universitário de Araraquara · BRHarvard University · USUniversidade de São Paulo · BR
Funding
Photodynamic Therapy of Localized InfectionsR01AI050875 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2003 to 2017
$4.8MSynergistic Photodynamic Therapy for Catherer-Associated Urinary Tract InfectionsR21AI121700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HAMBLIN, MICHAEL R · 2016 to 2017
$462kNIAID NIH HHS R01 AI050875NIAID NIH HHS R21 AI121700
Abstract
In recent years there have been an increasing number of
Indexed as
bacteriabiofilmsphotochemotherapyphotosensitizing agents
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT03483376ClinicalTrials.gov
NCT05162417ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.