Evidence map›Paper›PMID 29151701›Full record

Trial reportWorld journal of gastroenterology2017

Clinical outcomes of transcatheter selective superior mesenteric artery urokinase infusion therapy

Ting-Ting Jiang, Xiao-Ping Luo, Jian-Ming Sun, Jian Gao

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. [Exploration of pathogenesis and clinical diagnosis and treatment for portal vein thrombosis formation].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  10. [Consensus for management of portal vein thrombosis in liver cirrhosis (2020, Shanghai)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Congenital Thrombophilia in Patients With Superior Mesenteric Venous Thrombosis or Portal Vein Thrombosis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018
    Article
  16. Portal Vein Thrombosis in Cirrhosis.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ting-Ting JiangDepartment of Gastroenterology and Hepatology, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.
Xiao-Ping LuoDepartment of Radiology, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.
Jian-Ming SunDepartment of Vascular Surgery, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.
Jian GaoDepartment of Gastroenterology and Hepatology, Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China. ykdxdeyy@public.cta.cq.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare the outcomes of transcatheter superior mesenteric artery (SMA) urokinase infusion and transjugular intrahepatic portosystemic shunt (TIPS) for acute portal vein thrombosis (PVT) in cirrhosis.

methodsFrom January 2013 to December 2014, patients with liver cirrhosis and acute symptomatic PVT who met the inclusion criteria were randomly assigned to either an SMA group or a TIPS group. The two groups accepted transcatheter selective SMA urokinase infusion therapy and TIPS, respectively. The total follow-up time was 24 mo. The primary outcome measure was the change in portal vein patency status which was evaluated by angio-computed tomography or Doppler ultrasound. Secondary outcomes were rebleeding and hepatic encephalopathy.

resultsA total of 40 patients were enrolled, with 20 assigned to the SMA group and 20 to the TIPS group. The symptoms of all patients in the two groups improved within 48 h. PVT was improved in 17 (85%) patients in the SMA group and 14 (70%) patients in the TIPS group. The main portal vein (MPV) thrombosis was significantly reduced in both groups (

conclusionTranscatheter selective SMA urokinase infusion and TIPS are safe and effective for acute symptomatic PVT in cirrhosis.

Indexed as

Acute DiseaseAdultComputed Tomography AngiographyFemaleHepatic EncephalopathyHumansLiver CirrhosisMaleMesenteric Artery, SuperiorMiddle AgedPortal VeinPortasystemic Shunt, Transjugular IntrahepaticTreatment OutcomeUltrasonography, DopplerUrokinase-Type Plasminogen ActivatorVascular PatencyUrokinase-Type Plasminogen ActivatorCirrhosisPortal vein thrombosisSuperior mesenteric arteryTransjugular intrahepatic portosystemic shuntUrokinase

Identifiers

PMID29151701
PMCPMC5685853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.