Evidence map›Paper›PMID 29151658›Full record

ArticleJournal of the American Statistical Association2017

Generalized Scalar-on-Image Regression Models via Total Variation.

Xiao Wang, Hongtu Zhu

Abstract read
In one paragraph

Article in Journal of the American Statistical Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. High-dimensional partial linear model with trend filtering.Electronic journal of statistics · 2026
    Article
  3. Federated Function-on-function Regression with an Efficient Gradient Boosting Algorithm for Privacy-Preserving Telemedicine.IEEE transactions on automation science and engineering : a publication of the IEEE Robotics and Automation Society · 2026
    Article
  4. Article
  5. Article
  6. Spatial Adaptive Selection using Binary Conditional Autoregressive Model with Application to Brain-Computer Interface.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2025
    Article
  7. Article
  8. Article
  9. Multi-task Learning with High-Dimensional Noisy Images.Journal of the American Statistical Association · 2024
    Article
  10. Article
  11. Identifying regions of interest in mammogram images.Statistical methods in medical research · 2023
    Article
  12. Article
  13. Partially Observed Dynamic Tensor Response Regression.Journal of the American Statistical Association · 2023
    Article
  14. SCALAR ON NETWORK REGRESSION VIA BOOSTING.The annals of applied statistics · 2022
    Article
  15. Article
  16. Article
  17. High-Dimensional Spatial Quantile Function-on-Scalar Regression.Journal of the American Statistical Association · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xiao WangAssociate Professor of Statistics, Department of Statistics, Purdue University, West Lafayette, IN 47907.
Hongtu ZhuProfessor of Biostatistics, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, and University of North Carolina, Chapel Hill, NC 27599.

Funding

North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
Statistical Analysis of Biomedical Imaging Data in Curved SpaceR01MH086633 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI IBRAHIM, JOSEPH G · 2010 to 2018
$2.9M
National Science Foundation CMMI1030246National Science Foundation DMS1042967National Science Foundation DMS-1127914National Science Foundation DMS-1407655National Science Foundation SES-1357666NCATS NIH HHS UL1 TR001111NIMH NIH HHS R01 MH086633
6 · The paper itself

Abstract

The use of imaging markers to predict clinical outcomes can have a great impact in public health. The aim of this paper is to develop a class of generalized scalar-on-image regression models via total variation (GSIRM-TV), in the sense of generalized linear models, for scalar response and imaging predictor with the presence of scalar covariates. A key novelty of GSIRM-TV is that it is assumed that the slope function (or image) of GSIRM-TV belongs to the space of bounded total variation in order to explicitly account for the piecewise smooth nature of most imaging data. We develop an efficient penalized total variation optimization to estimate the unknown slope function and other parameters. We also establish nonasymptotic error bounds on the excess risk. These bounds are explicitly specified in terms of sample size, image size, and image smoothness. Our simulations demonstrate a superior performance of GSIRM-TV against many existing approaches. We apply GSIRM-TV to the analysis of hippocampus data obtained from the Alzheimers Disease Neuroimaging Initiative (ADNI) dataset.

Indexed as

Excess riskFunctional regressionGeneralized scalar-on-image regressionPredictionTotal variation

Identifiers

PMID29151658
PMCPMC5693263

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.